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产品信息
PA5-42004
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Hamster,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human FOLR1
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609391
产品详细信息
Peptide sequence: HFYFPTPTVL CNEIWTHSYK VSNYSRGSGR CIQMWFDPAQ GNPNEEVARF
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
靶标信息
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Adult folate-binding protein; FBP; folate binding protein; Folate receptor 1; folate receptor 1 (adult); Folate receptor alpha; Folate receptor, adult; FR-alpha; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18
基因别名: FBP; FOLR; FOLR1
UniProt ID: (Human) P15328
Entrez Gene ID: (Human) 2348
heart looping
neural crest cell migration involved in heart formation
cardiac neural crest cell migration involved in outflow tract morphogenesis
ER to Golgi vesicle-mediated transport
receptor-mediated endocytosis
folic acid transport
regulation of transforming growth factor beta receptor signaling pathway
axon regeneration
folic acid metabolic process
COPII vesicle coating
regulation of canonical Wnt signaling pathway
pharyngeal arch artery morphogenesis
anterior neural tube closure
cellular response to folic acid
