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Immunogen sequence: CPWVSYLPQP YAELEEVSSH VGKVFMARNY EFLAYEASKD RRQPLERMWT CNYNQQKDQS CNHKEITSTK A
Highest antigen sequence identity to the following orthologs: Mouse - 25%, Rat - 27%.
This gene encodes a protein that is an activator of the FAD-dependent enzyme D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder, possibly due to decreased levels of D-serine and decreased NMDA receptor functioning. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: D-amino acid oxidase regulator; G72 transcript; Protein G72; schizophrenia- and bipolar disorder-associated protein G72
基因别名: DAOA; G72; LG72; SG72
UniProt ID: (Human) P59103
Entrez Gene ID: (Human) 267012