Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-55600
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641823
产品详细信息
Immunogen sequence: ITRNTTPMYR TPEIIDLYSN FPIGEKQDIW ALGCILYLLC FRQHPFEDGA KLRIVNGKYS IPPHDTQYTV FH
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
靶标信息
GAK serine/threonine kinase or Cyclin-G-associated kinase was originally identified as a protein that is associated with cyclin G. However, neither CDK5 nor GAK kinase activity is activated by cyclin G nor does GAK affect CDK5 kinase activity. GAK seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: auxilin-2; Cyclin-G-associated kinase; DnaJ homolog subfamily C member 26
基因别名: DNAJ26; DNAJC26; GAK
UniProt ID: (Human) O14976
Entrez Gene ID: (Human) 2580
protein phosphorylation
receptor-mediated endocytosis
endoplasmic reticulum organization
Golgi organization
cell cycle
negative regulation of neuron projection development
clathrin coat disassembly
clathrin-mediated endocytosis
establishment of protein localization to Golgi
establishment of protein localization to plasma membrane
Golgi to lysosome transport
