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GALR1 Antibody (PA5-85250) in IHC (P)
Galanin receptor 1 antibody [C2C3], C-term detects galanin receptor 1 protein at membrane on human small intestine by immunohistochemical analysis. Sample: Paraffin-embedded small intestine. Galanin receptor 1 antibody [C2C3], C-term (Product # PA5-85250) dilutio. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-85250
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GALR1.
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792393
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Chicken (100%).
Positive Control: Synthetic peptide: 1:8,000.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gal receptor 1; Gal-1 receptor; Gal-r1; GAL1-R; Galanin r1 receptor; Galanin receptor type 1; Galanin-1 receptor; Galn1r; GALR-1; Hugal 1-r
基因别名: GALNR; GALNR1; GALR1
UniProt ID: (Human) P47211
Entrez Gene ID: (Human) 2587
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
digestion
positive regulation of transcription from RNA polymerase II promoter
positive regulation of cortisol secretion
