Invitrogen

GATA4 Polyclonal Antibody

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抗体检测数据 (3)

GATA4 Antibody in Western Blot (WB)

GATA4 Antibody in Western Blot (WB)

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GATA4 Antibody (PA5-11438) in WB

Western blot analysis of GATA4 in 293 cell lysates. Samples were incubated with GATA4 polyclonal antibody (Product # PA5-11438). Lysates: 2 µg/lane. 293 cell lysates either nontransfected (Lane 1) or transiently transfected with the GATA4 gene (Lane 2).

GATA4 Antibody in Western Blot (WB)

GATA4 Antibody in Western Blot (WB)

GATA4 Antibody in Flow Cytometry (Flow)

Product Image Gallery

GATA4 Antibody in Western Blot (WB) — Western blot analysis of GATA4 in 293 cell lysates. Samples were incubated with GATA4 polyclonal antibody (Product # PA5-11438). Lysates: 2 µg/lane. 293 cell lysates either nontransfected (Lane 1) or transiently transfected with the GATA4 gene (Lane 2).

GATA4 Antibody in Western Blot (WB) — Western blot analysis of GATA4 in CEM cell line lysates. Samples were incubated with GATA4 polyclonal antibody (Product # PA5-11438). Lysates: 35 µg/lane. GATA4(arrow).

GATA4 Antibody in Flow Cytometry (Flow) — Flow cytometry of GATA4 in HepG2 cells (right histogram). Samples were incubated with GATA4 polyclonal antibody (Product # PA5-11438) followed by FITC-conjugated goat-anti-rabbit secondary antibody. Negative control cell (left histogram).

产品信息

PA5-11438

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

-

流式细胞分析 (Flow)

1:10-1:50

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 298-328 amino acids from the C-terminal region of human GATA4

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2.0 mg/mL

纯化类型

Ammonium sulfate precipitation, Size-exclusion - Dialysis

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2108596

产品详细信息

This antibody is predicted to react with mouse, rat and Xenopus based on sequence homology.

靶标信息

GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in the gene encoding GATA4 have been associated with cardiac septal defects.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: GAT4; GATA-binding factor 4; MGC126629; Transcription factor GATA-4

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基因别名: ASD2; GATA4; TACHD; TOF; VSD1

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UniProt ID: (Human) P43694

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Entrez Gene ID: (Human) 2626

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RNA polymerase II regulatory region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding RNA polymerase II transcription factor binding enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding zinc ion binding protein kinase binding activating transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding NFAT protein binding co-SMAD binding DNA-binding transcription factor

参与通路

heart looping endocardial cushion development cardiac ventricle morphogenesis cardiac right ventricle morphogenesis ventricular septum development atrial septum primum morphogenesis atrial septum secundum morphogenesis regulation of transcription, DNA-templated transcription from RNA polymerase II promoter cell-cell signaling endoderm development blood coagulation male gonad development response to mechanical stimulus negative regulation of autophagy positive regulation of vascular endothelial growth factor production positive regulation of BMP signaling pathway response to vitamin A embryonic heart tube anterior/posterior pattern specification response to drug cell fate commitment positive regulation of angiogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cell development embryonic foregut morphogenesis anatomical structure formation involved in morphogenesis positive regulation of cardioblast differentiation transdifferentiation atrial septum morphogenesis intestinal epithelial cell differentiation cell growth involved in cardiac muscle cell development cellular response to glucose stimulus regulation of cardiac muscle cell contraction