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产品信息
MA1-725
产品规格
种属反应
Bovine
已发表种属
Bovine
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
A1
抗原
Bacterial expressed full length GCAP-2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2263831
产品详细信息
MA1-725 detects GCAP-2 from bovine samples. This antibody is specific for GCAP-2 and does not react with other isotypes.
MA1-725 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~23 kDa protein representing GCAP-2 protein in bovine samples.
The MA1-725 immunogen is bacterial expressed full length GCAP-2.
靶标信息
Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin superfamily. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP-1 and GCAP-2. It has been demonstrated that both GCAP-1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP-1 is predominantly localized in the photoreceptor outer segments, while GCAP-2 is found in retina samples.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DKFZp686E1183; GCAP 2; Guanylate cyclase activator 1B; guanylate cyclase activator 1B (retina); Guanylin 2; Guanylyl cyclase-activating protein 2; GUCA 2; Retinal guanylyl cyclase activator protein p24
基因别名: GCAP-2; GCAP2; GUCA1B
UniProt ID: (Bovine) P51177
Entrez Gene ID: (Bovine) 286851
