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GCC2 Antibody (PA5-89457) in IHC (P)
Immunohistochemistry analysis of GCC2 in paraffin-embedded human appendix. Samples were incubated with GCC2 Polyclonal antibody (Product # PA5-89457) using a dilution of 1:150 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-89457
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCC2 (NP_8521181)
偶联物
Unconjugated
形式
Liquid
浓度
1.98 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2805580
产品详细信息
Immunogen sequence: MEDLVQDGVA SPATPGTGKS KLETLPKEDL IKFAKKQMML IQKAKSRCTE LEKEIEELRS KPVTEGTGDI IKALTERLDA LLLEKAETEQ QCLSLKKENI KMKQEVEDSV TKMGDAHKEL EQSHINYVKE IENLKNELMA VRSKYSEDKA NLQKQLEEAM NTQLELSEQL KFQNNSEDNV KKLQEEIEKI RPGFEEQILY LQKQLDATTD EKKETVTQLQ NIIEANSQHY QKNINSLQEE LLQLKAIHQE EVKELMCQIE ASAKEHEAEI NKLNELKENL VKQCEASEKN IQKKYECELE; Positive Samples: HeLa, LO2, 22Rv1, Raji, SGC-7901, 293T; Cellular Location: Cytoplasm, Golgi apparatus, Peripheral membrane protein, trans-Golgi network membrane
靶标信息
The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 185 kDa Golgi coiled-coil protein; CLL-associated antigen KW-11; CTCL tumor antigen se1-1; GCC protein, 185-kD; GCC185; Golgi coiled-coil protein GCC185; GRIP and coiled-coil domain-containing protein 2; Ran-binding protein 2-like 4; RanBP2L4; Renal carcinoma antigen NY-REN-53
基因别名: 0610043A03Rik; 2210420P05Rik; 2600014C01Rik; AW112121; GCC185; GCC2; KIAA0336; mKIAA0336; RANBP2L4; REN53
UniProt ID: (Human) O15045, (Mouse) Q8CHG3
Entrez Gene ID: (Human) 9648, (Mouse) 70297
protein targeting to Golgi
protein targeting to lysosome
microtubule organizing center organization
protein localization to Golgi apparatus
microtubule anchoring
late endosome to Golgi transport
retrograde transport, endosome to Golgi
Golgi to plasma membrane protein transport
regulation of protein exit from endoplasmic reticulum
recycling endosome to Golgi transport
Golgi ribbon formation
transport
protein transport
