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GFM1 Antibody (PA5-103825) in ICC/IF
Immunocytochemistry analysis of GFM1 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with GFM1 polyclonal antibody (Product # PA5-103825) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-103825
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human GFM1(Accession Q96RP9), corresponding to amino acid residues E682-I732.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853158
产品详细信息
Antibody detects endogenous levels of total GFM1.
靶标信息
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EF-Gmt; Elongation factor G 1, mitochondrial; Elongation factor G, mitochondrial; Elongation factor G1; G elongation factor, mitochondrial 1; G translation elongation factor, mitochondrial; GFM1; hEFG1; mEF-G 1; mitochondrial elongation factor G; mitochondrial elongation factor G1
基因别名: COXPD1; EFG; EFG1; EFGM; EGF1; GFM; GFM1; hEFG1
UniProt ID: (Human) Q96RP9
Entrez Gene ID: (Human) 85476
