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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGPAGVAARP GRFFGVYLLY CLNPRYRGRV YVGFTVNTAR RVQQHNGGRK KGGAWRTSGR GPWEMVLVVH GFPSSVAALR FEWAWQHPHA SRRLAHVGPR LRGETAFAFH LRVLAHMLRA PPWARLPLTL RWVRPDLRQD LCLPPPPHVP LAFGPPPPQA PAPRRRAGPF DDAEPEPDQG DPGACCSLCA QTIQDEEGPL CCPHPGCLLR AHVICLAEEF LQEEPGQLLP LEGQCPCCEK SLLWGDLIWL CQMDTEKEVE DSELEEAHWT DLLET
This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GIY-YIG domain-containing protein 1; SLX1 homolog B; SLX1 structure-specific endonuclease subunit homolog B; SLX1A; SLX1B; Structure-specific endonuclease subunit SLX1
基因别名: GIYD1; GIYD2; SLX1; SLX1A; SLX1B
UniProt ID: (Human) Q9BQ83
Entrez Gene ID: (Human) 79008
分子生物学功能:
endodeoxyribonuclease