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产品信息
MA5-50087
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG4
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
7H7
抗原
Recombinant Human GLP1R protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_3093061
靶标信息
Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GLP-1 receptor; GLP-I receptor; GLP1 receptor; Glucagon-like peptide 1 receptor; glucagon-like peptide-1 receptor; seven transmembrane helix receptor
基因别名: GLP-1; GLP-1-R; GLP-1R; GLP1R
UniProt ID: (Human) P43220
Entrez Gene ID: (Human) 2740
response to stress
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
learning or memory
regulation of heart contraction
cAMP-mediated signaling
positive regulation of blood pressure
regulation of insulin secretion
cellular response to glucagon stimulus
