Invitrogen

GLP1R Recombinant Rabbit Monoclonal Antibody (HL2297)

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GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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GLP1R Antibody (MA5-50480) in IHC (P)

Immunohistochemical analysis of GLP1R using GLP1R Recombinant Monoclonal Antibody (Product # MA5-50480) in Paraffin embedded mouse pancreas tissue at a dilution of 1:20,000. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of GLP1R using GLP1R Recombinant Monoclonal Antibody (Product # MA5-50480) in Paraffin embedded mouse pancreas tissue at a dilution of 1:20,000. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of GLP1R using GLP1R Recombinant Monoclonal Antibody (Product # MA5-50480) in Paraffin embedded human pancreas tissue at a dilution of 1:200. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of GLP1R using GLP1R Recombinant Monoclonal Antibody (Product # MA5-50480) in Paraffin embedded mouse pancreas tissue at a dilution of 1:200. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

GLP1R Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of GLP1R using GLP1R Recombinant Monoclonal Antibody (Product # MA5-50480) in Paraffin embedded rat pancreas tissue at a dilution of 1:200. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

产品信息

MA5-50480

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

Assay-dependent

-

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

HL2297

抗原

Synthetic peptide of human GLP1R.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_3093037

靶标信息

Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: GLP-1 receptor; GLP-1-R; GLP-I receptor; Glucagon-like peptide 1 receptor

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基因别名: GLP-1R; Glp1r; GLP1Rc

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UniProt ID: (Mouse) O35659

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Entrez Gene ID: (Mouse) 14652

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peptide receptor activity signal transducer activity receptor activity transmembrane signaling receptor activity G-protein coupled receptor activity glucagon receptor activity G-protein coupled peptide receptor activity peptide hormone binding transmembrane signal receptor

参与通路

response to stress signal transduction cell surface receptor signaling pathway G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration neuropeptide signaling pathway learning or memory memory feeding behavior regulation of heart contraction positive regulation of cell proliferation associative learning response to glucose cAMP-mediated signaling insulin secretion positive regulation of insulin secretion negative regulation of apoptotic process negative regulation of neuron apoptotic process positive regulation of cell differentiation positive regulation of blood pressure positive regulation of heart contraction positive regulation of transcription from RNA polymerase II promoter hormone secretion release of sequestered calcium ion into cytosol regulation of calcium ion transport