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This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bA500G10.4; FLJ11864; glutaredoxin 4; Glutaredoxin-3; PICOT; PKC interacting cousin of thioredoxin; PKC-interacting cousin of thioredoxin; PKC-theta-interacting protein; PKCq-interacting protein; testicular tissue protein Li 75; thioredoxin-like 2; Thioredoxin-like protein 2
基因别名: GLRX3; GLRX4; GRX3; GRX4; HUSSY-22; PICOT; TXNL2; TXNL3
UniProt ID: (Human) Q9P1B1, (Mouse) Q9CQM9
Entrez Gene ID: (Human) 10539, (Mouse) 30926