Invitrogen

GLUT2 Polyclonal Antibody

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GLUT2 Antibody (PA5-97263) in WB

Western blot was performed using GLUT2 Polyclonal Antibody (Product # PA5-97263) and a 55 kDa, 60 kDa band corresponding to Slc2a2 was observed across cell lines tested. Membrane enriched extracts (30 µg lysate) of Hep G2 (Lane 1), Hep G2 treated with Insulin (5 µM for 4hrs) (Lane 2), Caco-2 (Lane 3), A-431 (Lane 4), A549 (Lane 5) and 769-P (Lane 6) as seen in (Fig. a) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX), 12 well. Resolved proteins were then transferred onto a nitrocellulose membrane (Product... View More

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产品信息

PA5-97263

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:500

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免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLUT2/GLUT2/SLC2A2 (NP_0003311)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.35 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2809065

产品详细信息

Positive Samples: SW480, THP-1, Mouse liver, Mouse kidney, Rat liver; Cellular Location: Membrane, Multi-pass membrane protein

Immunogen sequence: YVINSTDELP TISYSMN

靶标信息

Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in the gene that encode this protein cause Fanconi-Bickel syndrome.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Singular versus combinatory glucose-sensitive signal control of metabolic sensor protein profiles in hypothalamic astrocyte cultures from each sex.

Translational neuroscience

Alhamyani A,Napit PR,Bheemanapally K,Sylvester PW,Briski KP

PA5-97263 was used in Western Blot, Immunohistochemistry to show that DEX and NE regulation of GLUT2 is sex-monomorphic, but both stimuli impose divergent sex-specific effects on AMPK and pAMPK.

Sat Jan 01 00:00:00 EST 2022

生物信息学

蛋白别名: glucose transporter 2; Glucose transporter type 2, liver; GLUT-2; liver-type glucose transporter; solute carrier family 2 (facilitated glucose transporter), member 2; Solute carrier family 2, facilitated glucose transporter member 2

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基因别名: AI266973; Glut-2; GLUT2; GTT2; SLC2A2

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UniProt ID: (Human) P11168, (Mouse) P14246

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Entrez Gene ID: (Human) 6514, (Mouse) 20526, (Rat) 25351

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功能

insulin receptor binding glucose transmembrane transporter activity hexose transmembrane transporter activity dehydroascorbic acid transporter activity D-glucose transmembrane transporter activity transporter activity sugar:proton symporter activity transmembrane transporter activity substrate-specific transmembrane transporter activity

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