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产品信息
PA5-20693
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
An 18 amino acid peptide near the carboxy terminus of human GNPDA1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11153690
产品详细信息
A suggested positive control is mouse kidney tissue lysate.
PA5-20693 can be used with blocking peptide PEP-0808.
靶标信息
GNPDA1 is a 289 amino acid cytoplasmic protein belonging to the glucosamine/ galactosamine-6-phosphate isomerase family. It is one of the two mammalian glucosamine-6-phosphate deaminase enzymes. GNPDA1 is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate (GlcN6P) into D-fructose-6-phosphate (Fru6P) and ammonium with an aldo/keto isomerization and an amination/deamination. GNPDA1 may trigger calcium oscillations in mammalian eggs at fertilization which in turn serve as an important factor for egg development and early embryo development. It is a homohexamer, ubiquitously expressed in most of human tissues with high expression in testis, ovary, placenta, and heart and also in various cell lines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glcN6P deaminase 1; Glucosamine-6-phosphate deaminase 1; Glucosamine-6-phosphate isomerase 1; glucose-6-phosphate isomerase; GNPDA 1; Oscillin
基因别名: GNP1; GNPDA; GNPDA1; GNPI; GPI; HLN; KIAA0060; oscillin
UniProt ID: (Human) P46926, (Mouse) O88958
Entrez Gene ID: (Human) 10007, (Mouse) 26384, (Rat) 683570
glucose metabolic process
glucosamine catabolic process
N-acetylglucosamine catabolic process
UDP-N-acetylglucosamine biosynthetic process
generation of precursor metabolites and energy
single fertilization
N-acetylneuraminate catabolic process
carbohydrate metabolic process
fructose 6-phosphate metabolic process
glucosamine metabolic process
N-acetylglucosamine metabolic process
acrosome reaction
fructose biosynthetic process
