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Invitrogen
GPI Polyclonal Antibody
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Product Details
PA5-87284
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human GPI.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMF; Autocrine motility factor; glucose phosphate isomerase; glucose phosphate isomerase 1 complex; glucose phosphate isomerase 1, regulatory; glucose phosphate isomerase 1, structural; glucose phosphate isomerase 1, temporal; Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase {ECO:0000250|UniProtKB:P06745}; GPI; GPI {ECO:0000250|UniProtKB:P06745}; gpi {ECO:0000312|RGD:2727}; hexose monophosphate isomerase; hexosephosphate isomerase; maturation factor; Neuroleukin; neuroleukin {ECO:0000250|UniProtKB:P06745}; NLK; NLK {ECO:0000250|UniProtKB:P06745}; oxoisomerase; PGI; PGI {ECO:0000250|UniProtKB:P06745}; PHI; PHI {ECO:0000250|UniProtKB:P06745}; Phosphoglucose isomerase; phosphoglucose isomerase {ECO:0000250|UniProtKB:P06745}; phosphohexomutase; Phosphohexose isomerase; phosphohexose isomerase {ECO:0000250|UniProtKB:P06745}; phosphosaccharomutase; SA-36; sperm antigen; Sperm antigen 36; sperm antigen-36
Gene Aliases: AMF; GNPI; GPI; Gpi-1; Gpi-1r; Gpi-1s; Gpi-1t; Gpi1; Gpi1-r; Gpi1-s; Gpi1-t; Gpi1s; MF; NK; NK/GPI; NLK; Org; PGI; PHI; SA-36; SA36
UniProt ID: (Human) P06744, (Rat) Q6P6V0, (Mouse) P06745
Entrez Gene ID: (Human) 2821, (Rat) 292804, (Mouse) 14751
angiogenesis
in utero embryonic development
mesoderm formation
carbohydrate metabolic process
gluconeogenesis
humoral immune response
hemostasis
learning or memory
methylglyoxal biosynthetic process
erythrocyte homeostasis
glucose homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
aldehyde catabolic process
glucose 6-phosphate metabolic process
canonical glycolysis
glycolytic process
glycolytic process through glucose-6-phosphate
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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