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产品信息
MA5-25101
产品规格
种属反应
Human,
Rhesus monkey
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2D2
抗原
Full length human recombinant protein of GPI produced in HEK293T cell
偶联物
形式
Liquid
浓度
0.68 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2724385
靶标信息
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
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生物信息学
蛋白别名: AMF; Autocrine motility factor; glucose phosphate isomerase; Glucose-6-phosphate isomerase; GPI; hexose monophosphate isomerase; hexosephosphate isomerase; Neuroleukin; NLK; oxoisomerase; PGI; PHI; Phosphoglucose isomerase; phosphohexomutase; Phosphohexose isomerase; phosphosaccharomutase; SA-36; sperm antigen; Sperm antigen 36; sperm antigen-36
基因别名: AMF; GNPI; GPI; NLK; PGI; PHI; SA-36; SA36
UniProt ID: (Human) P06744
Entrez Gene ID: (Rhesus monkey) 717980, (Human) 2821
angiogenesis
in utero embryonic development
mesoderm formation
carbohydrate metabolic process
gluconeogenesis
humoral immune response
hemostasis
learning or memory
methylglyoxal biosynthetic process
erythrocyte homeostasis
glucose homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
aldehyde catabolic process
glucose 6-phosphate metabolic process
canonical glycolysis
