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产品信息
PA1-32512
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GPR116
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2279242
产品详细信息
PA1-32512 detects GPCR GPR116 from human samples.
靶标信息
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain and three Ig-like domains and belongs to the GPR family. Existing as a dilsulfide-liked homodimer at the cell surface, GPR116 exists as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.
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生物信息学
蛋白别名: Adhesion G protein-coupled receptor F5; DKFZp564O1923; FLJ90640; G protein-coupled receptor 116; G-protein coupled receptor 116; Ig-Hepta homolog; probable G-protein coupled receptor 116
基因别名: ADGRF5; GPR116; KIAA0758; KPG_001
UniProt ID: (Human) Q8IZF2
Entrez Gene ID: (Human) 221395
