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Product Details
H00011245-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GPR176 (NP_009154.1, 1 a.a. approximately 515 a.a) full-length human protein.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGHNGSWISP NASEPHNASG AEAAGVNRSA LGEFGEAQLY RQFTTTVQVV IFIGSLLGNF MVLWSTCRTT VFKSVTNRFI KNLACSGICA SLVCVPFDII LSTSPHCCWW IYTMLFCKVV KFLHKVFCSV TILSFPAIAL DRYYSVLYPL ERKISDAKSR ELVMYIWAHA VVASVPVFAV TNVADIYATS TCTEVWSNSL GHLVYVLVYN ITTVIVPVVV VFLFLILIRR ALSASQKKKV IIAALRTPQN TISIPYASQR EAELHATLLS MVMVFILCSV PYATLVVYQT VLNVPDTSVF LLLTAVWLPK VSLLANPVLF LTVNKSVRKC LIGTLVQLHH RYSRRNVVST GSGMAEASLE PSIRSGSQLL EMFHIGQQQI FKPTEDEEES EAKYIGSADF QAKEIFSTCL EGEQGPQFAP SAPPLSTVDS VSQVAPAAPV EPETFPDKYS LQFGFGPFEL PPQWLSETRN SKKRLLPPLG NTPEELIQTK VPKVGRVERK MSRNNKVSIF PKVDS
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR176 (G protein-coupled receptor 176), also known as HB-954, GPR or Gm1012, is a 515 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. Expressed in brain and spleen, with trace expression in kidney, GPR176 functions as an orphan receptor that is thought to play a role in signaling events throughout the cell. Containing four N-glycosylation sites, seven transmembrane domains and a large C-terminal cytosolic domain, GPR176 is encoded by a gene mapping to human chromosome 15q14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor 176; HB-954; HB954
Gene Aliases: GPR176; HB-954
UniProt ID: (Human) Q14439
Entrez Gene ID: (Human) 11245
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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