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产品信息
PA5-33706
产品规格
种属反应
Horse,
Human,
Mouse,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 3rd extracellular domain of human GPR39.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551081
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Horse, Rabbit (100%) Marmoset, Bovine, Panda, Turkey, Chicken (94%).
靶标信息
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. G protein-coupled receptor 39 is an orphan receptor in the Ghrelin family pathway. Various studies have shown that GPR39 plays important roles in hypertension, adipogenesis and that overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G-protein coupled receptor 39
基因别名: 4933415E13Rik; GPR39
UniProt ID: (Human) O43194
Entrez Gene ID: (Horse) 100054142, (Human) 2863, (Rabbit) 103348824, (Mouse) 71111, (Rat) 288995
G-protein coupled receptor signaling pathway
diet induced thermogenesis
signal transduction
adult feeding behavior
regulation of lipid metabolic process
positive regulation of insulin secretion
gastric emptying
positive regulation of insulin secretion involved in cellular response to glucose stimulus
regulation of membrane potential
glucose homeostasis
cholesterol homeostasis
positive regulation of release of sequestered calcium ion into cytosol
negative regulation of gastric acid secretion
cellular response to zinc ion
