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Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%); Mouse, Rat, Dog, Bovine, Elephant, Panda, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Xenopus, Pufferfish, Zebrafish, Stickleback (94%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A-69G12.1; G protein-coupled receptor, class C, group 5, member B; G protein-coupled receptor, family C, group 1, member B; G-protein coupled receptor family C group 5 member B; RAIG-2; retinoic acid responsive gene protein; Retinoic acid-induced gene 2 protein
基因别名: GPRC5B; RAIG-2; RAIG2
UniProt ID: (Human) Q9NZH0
Entrez Gene ID: (Human) 51704
分子生物学功能:
G-protein coupled receptor