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GRB7 Antibody (PA5-102994) in IHC (P)
Immunohistochemistry analysis of GRB7 in mouse liver tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with GRB7 polyclonal antibody (Product # PA5-102994) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-102994
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human GRB7(Accession Q14451), corresponding to amino acid residues V286-F336.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852366
产品详细信息
Antibody detects endogenous levels of total GRB7.
靶标信息
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B47; Epidermal growth factor receptor GRB-7; GRB7 adapter protein; growth factor receptor binding protein GRB7; Growth factor receptor-bound protein 7; OTTHUMP00000164352
基因别名: GRB7
UniProt ID: (Human) Q14451, (Rat) Q9QZC5
Entrez Gene ID: (Human) 2886, (Rat) 84427
