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GREM2 Antibody (H00064388-B01P) in WB
Western Blot analysis of GREM2 expression in transfected 293T cell line (H00064388-T01) by GREM2 MaxPab polyclonal antibody.
Lane 1: GREM2 transfected lysate(18.48 KDa).
Lane 2: Non-transfected lysate.
Lane 1: GREM2 transfected lysate(18.48 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00064388-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GREM2 (AAH46632.1, 1 a.a. approximately 168 a.a) full-length human protein.
偶联物
Unconjugated
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MFWKLSLSLF MVAVLVKVAE ARKNRPAGAI HSPYKDGSSN NSERWQHQIK EVLASSQEAL VVTERKYLKS DWCKTQPLRQ TVSEEGCRSR TILNRFCYGQ CNSFYIPRHV KKEEESFQSC AFCKPQRVTS VLVELECPGL DPPFRLKKIQ KVKQCRCMSV NLSDSDKQ
靶标信息
GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CKTSF1B2FLJ21195; Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; DAND3Prdc; gremlin 2, cysteine knot superfamily, homolog; Gremlin-2; PRDCgremlin 2; Protein related to DAN and cerberus
基因别名: CKTSF1B2; DAND3; GREM2; PRDC
UniProt ID: (Human) Q9H772
Entrez Gene ID: (Human) 64388
