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GREM2 Antibody (PA5-78559) in IHC (P)
GREM2 Polyclonal Antibody detects GREM2 protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. GREM2 Polyclonal Antibody (Product # PA5-78559) dilution: 1:100. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-78559
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GREM2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.26 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2735881
产品详细信息
Positive Control: A549, IMR32
Predicted Reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CKTSF1B2FLJ21195; Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; DAND3Prdc; gremlin 2, cysteine knot superfamily, homolog; Gremlin-2; PRDCgremlin 2; Protein related to DAN and cerberus
基因别名: CKTSF1B2; DAND3; GREM2; PRDC
UniProt ID: (Human) Q9H772
Entrez Gene ID: (Human) 64388
