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产品信息
PA5-41616
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human GRHL3
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2606412
产品详细信息
Peptide sequence: EEVFDALMLK TPDLKGLRNA ISEKYGFPEE NIYKVYKKCK RGILVNMDNN
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 100%; Rat: 93%
靶标信息
This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Grainyhead-like protein 3 homolog; Sister of mammalian grainyhead; sister-of-mammalian grainyhead; Transcription factor CP2-like 4; transcription factor hSOM1
基因别名: GRHL3; SOM; TFCP2L4; VWS2
UniProt ID: (Human) Q8TE85
Entrez Gene ID: (Human) 57822
establishment of planar polarity
neural tube closure
transcription from RNA polymerase II promoter
pattern specification process
ectoderm development
central nervous system development
epidermis development
regulation of actin cytoskeleton organization
wound healing
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
eyelid development in camera-type eye
establishment of skin barrier
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
