Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 8
GRHL3 Antibody (PA5-66299) in ICC/IF
Immunofluorescent staining of GRHL3 in human cell line MCF7 shows localization to nucleoplasm. Samples were probed using a GRHL3 Polyclonal Antibody (Product # PA5-66299).
产品信息
PA5-66299
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
形式
Liquid
浓度
0.10 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2664197
产品详细信息
Immunogen sequence: VNGDDDSVAAL SFLYDYYMGP KEKRILSSST GGRNDQGKRY YHGMEYETDL TPLESPTHLM KFLTENVSGT PEYPDLLKKN NLMSL
Highest antigen sequence identity to the following orthologs - mouse 84%, rat 86%.
靶标信息
This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Grainyhead-like protein 3 homolog; Sister of mammalian grainyhead; sister-of-mammalian grainyhead; Transcription factor CP2-like 4; transcription factor hSOM1
基因别名: GRHL3; SOM; TFCP2L4; VWS2
UniProt ID: (Human) Q8TE85
Entrez Gene ID: (Human) 57822
establishment of planar polarity
neural tube closure
transcription from RNA polymerase II promoter
pattern specification process
ectoderm development
central nervous system development
epidermis development
regulation of actin cytoskeleton organization
wound healing
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
eyelid development in camera-type eye
establishment of skin barrier
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
