Invitrogen

GRK6 Polyclonal Antibody

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抗体检测数据 (1)

GRK6 Antibody in Immunocytochemistry (ICC/IF)

GRK6 Antibody in Immunocytochemistry (ICC/IF)

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GRK6 Antibody (PA5-49806) in ICC/IF

Immunocytochemical analysis of GRK6 in Hela cells, using GRK6 Polyclonal Antibody (Product # PA5-49806).

GRK6 Antibody in Immunocytochemistry (ICC/IF)

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GRK6 Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemical analysis of GRK6 in Hela cells, using GRK6 Polyclonal Antibody (Product # PA5-49806).

产品信息

PA5-49806

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

-

免疫细胞化学 (ICC/IF)

1:100-1:500

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthesized peptide derived from N-terminal of human GRK6.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

RRID

AB_2635259

产品详细信息

The antibody detects endogenous levels of total GRK6 protein.

靶标信息

GRK6 is a member of the guanine nucleotide-binding protein coupled receptor kinase subfamily of the serine/threonine protein kinase family. GRK6 phosphorylates the activated forms of G protein-coupled receptors to initiate their deactivation. Several transcript variants encoding different isoforms have been described for GRK6.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: EC 2.7.11.16; G protein-coupled receptor kinase 6; G protein-coupled receptor kinase GRK6; G-protein coupled receptor kinase 6; kinase GRK6

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基因别名: GPRK6; GRK6

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UniProt ID: (Human) P43250, (Mouse) O70293

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Entrez Gene ID: (Human) 2870, (Mouse) 26385, (Rat) 59076

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G-protein coupled receptor kinase activity protein binding ATP binding beta-adrenergic receptor kinase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups non-receptor serine/threonine protein kinase

参与通路

desensitization of G-protein coupled receptor protein signaling pathway protein phosphorylation regulation of G-protein coupled receptor protein signaling pathway negative regulation of anion channel activity Wnt signaling pathway signal transduction phosphorylation termination of G-protein coupled receptor signaling pathway