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This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Gasdermin-B; Gasdermin-like protein
基因别名: GSDMB; GSDML; PP4052; PRO2521
UniProt ID: (Human) Q8TAX9
Entrez Gene ID: (Human) 55876