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GSTP1 Antibody (PA5-29601) in ICC/IF
GSTP1 Polyclonal Antibody detects GSTP1 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: GSTP1 stained by GSTP1 Polyclonal Antibody (Product # PA5-29601) diluted at 1:500. Blue: Fluoroshield with DAPI .
产品信息
PA5-29601
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 176 of Human GSTP1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547077
产品详细信息
Recommended positive controls: HeLa, Molt-4, mouse brain, Rat brain.
Predicted reactivity: Mouse (82%), Rat (86%), Dog (86%), Rhesus Monkey (97%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Chain 7; deafness, X-linked 7; epididymis secretory protein Li 22; fatty acid ethyl ester synthase III; Glutathione S-transferase P; Glutathione S-transferase P 1; glutathione S-transferase pi 2; glutathione S-transferase, pi 2; Glutathione-S-transferase placental enzyme pi type; glutathione-S-transferase, pi 1; Glutathione-S-transferase, placental enzyme pi type; GST 7-7; GST class-pi; Gst p-1; Gst P1; GST YF-YF; GST-piB; GSTP1-1; HGNC:4638; Preadipocyte growth factor
基因别名: DFN7; FAEES3; GST-P; GST3; GSTP; GSTP1; Gstp2; GstpiB; HEL-S-22; PI
UniProt ID: (Human) P09211, (Rat) P04906, (Mouse) P19157
Entrez Gene ID: (Human) 2950, (Rat) 24426, (Mouse) 14870
response to reactive oxygen species
negative regulation of acute inflammatory response
negative regulation of protein kinase activity
glutathione metabolic process
xenobiotic metabolic process
central nervous system development
negative regulation of biosynthetic process
negative regulation of tumor necrosis factor-mediated signaling pathway
oligodendrocyte development
organ regeneration
response to estradiol
negative regulation of interleukin-1 beta production
negative regulation of tumor necrosis factor production
cellular response to insulin stimulus
regulation of stress-activated MAPK cascade
negative regulation of stress-activated MAPK cascade
positive regulation of superoxide anion generation
response to L-ascorbic acid
common myeloid progenitor cell proliferation
nitric oxide storage
negative regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to amino acid
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
negative regulation of JUN kinase activity
linoleic acid metabolic process
response to ethanol
response to mercury ion
negative regulation of fibroblast proliferation
negative regulation of nitric-oxide synthase biosynthetic process
regulation of ERK1 and ERK2 cascade
negative regulation of ERK1 and ERK2 cascade
negative regulation of leukocyte proliferation
cellular response to lipopolysaccharide
cellular response to epidermal growth factor stimulus
cellular response to glucocorticoid stimulus
cellular response to cell-matrix adhesion
negative regulation of monocyte chemotactic protein-1 production
cellular oxidant detoxification
glutathione derivative biosynthetic process
negative regulation of extrinsic apoptotic signaling pathway
response to toxic substance
response to nutrient levels
negative regulation of peroxidase activity
metabolic process
negative regulation of neutrophil aggregation
