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GSTP1 Antibody (MA5-34932) in IHC (P)
Immunohistochemistry analysis of GST3 in paraffin-embedded human thyroid gland tissue. Samples were heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4, 20 minutes) and blocked in 5% BSA (30 min, room temperature), incubated with GST3 monoclonal antibody (Product # MA5-34932) at a dilution of 1:200 (30 min, room temperature), and followed by HRP conjugate, DAB and hematoxylin (mounted with DPX... View More
产品信息
MA5-34932
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
11D5
抗原
Recombinant protein within Human GST3 aa 1-183
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2848838
产品详细信息
Positive Control: A549, rat kidney tissue, human thyroid gland tissue, human breast cancer tissue, human placenta tissue, mouse lung tissue, HCT116.
靶标信息
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: deafness, X-linked 7; epididymis secretory protein Li 22; fatty acid ethyl ester synthase III; Glutathione S-transferase P; GST class-pi; GSTP1-1; HGNC:4638
基因别名: DFN7; FAEES3; GST3; GSTP; GSTP1; HEL-S-22; PI
UniProt ID: (Human) P09211
Entrez Gene ID: (Human) 2950
response to reactive oxygen species
negative regulation of acute inflammatory response
negative regulation of protein kinase activity
glutathione metabolic process
xenobiotic metabolic process
central nervous system development
negative regulation of biosynthetic process
negative regulation of tumor necrosis factor-mediated signaling pathway
oligodendrocyte development
organ regeneration
response to estradiol
negative regulation of interleukin-1 beta production
negative regulation of tumor necrosis factor production
cellular response to insulin stimulus
regulation of stress-activated MAPK cascade
negative regulation of stress-activated MAPK cascade
positive regulation of superoxide anion generation
response to L-ascorbic acid
common myeloid progenitor cell proliferation
nitric oxide storage
negative regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to amino acid
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
negative regulation of JUN kinase activity
linoleic acid metabolic process
response to ethanol
response to mercury ion
negative regulation of fibroblast proliferation
negative regulation of nitric-oxide synthase biosynthetic process
regulation of ERK1 and ERK2 cascade
negative regulation of ERK1 and ERK2 cascade
negative regulation of leukocyte proliferation
cellular response to lipopolysaccharide
cellular response to epidermal growth factor stimulus
cellular response to glucocorticoid stimulus
cellular response to cell-matrix adhesion
negative regulation of monocyte chemotactic protein-1 production
cellular oxidant detoxification
glutathione derivative biosynthetic process
negative regulation of extrinsic apoptotic signaling pathway
