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GSTT1 Antibody (PA5-22011) in IHC (P)
GSTT1 Polyclonal Antibody detects GSTT1 protein at cytosol on human hepatoma by immunohistochemical analysis. Sample: Paraffin-embedded human hepatoma. GSTT1 Polyclonal Antibody (Product # PA5-22011) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-22011
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Full length human GSTT1 Recombinant protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycerine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11154445
产品详细信息
Recommended positive controls: HepG2, mouse spleen, rat liver.
Predicted reactivity: Mouse (81%), Rat (80%), Rhesus Monkey (97%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glutathione S-transferase 1 (theta); Glutathione S-transferase 5; Glutathione S-transferase theta-1; Glutathione transferase T1-1; GST 5-5; GST class-theta-1
基因别名: AI255817; GSTT1; Gstt1-1; GSTYRS
UniProt ID: (Human) P30711, (Rat) Q01579, (Mouse) Q64471
Entrez Gene ID: (Human) 2952, (Rat) 25260, (Mouse) 14871
glutathione metabolic process
cellular oxidant detoxification
glutathione derivative biosynthetic process
DNA modification
response to salicylic acid
response to selenium ion
response to organic cyclic compound
dichloromethane metabolic process
response to vitamin E
response to drug
oxidation-reduction process
