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GSTT1 Antibody (PA5-79341) in WB
Western blot analysis of GSTT1 in Lane 1: rat liver tissue lysate, Lane 2: rat lung tissue lysate, Lane 3: mouse liver tissue lysate, Lane 4: mouse lung tissue lysate using 50 µg (reducing conditions) per well. Electrophoresis was performed on 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours and protein was transferred to a nitrocellulose membrane at 150mA for 50-90 minutes. Sample was blocked with 5% Non-fat Milk/TBS for 1.5 hours at room temperature, incubated with GSTT1 polyclonal antibody (Product # PA5-7934... View More
产品信息
PA5-79341
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human GSTT1 recombinant protein (Position: L3-L231).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2746457
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glutathione S-transferase 1 (theta); Glutathione S-transferase 5; Glutathione S-transferase theta-1; Glutathione transferase T1-1; GST 5-5; GST class-theta-1
基因别名: AI255817; GSTT1; Gstt1-1; GSTYRS
UniProt ID: (Human) P30711, (Rat) Q01579, (Mouse) Q64471
Entrez Gene ID: (Human) 2952, (Rat) 25260, (Mouse) 14871
glutathione metabolic process
cellular oxidant detoxification
glutathione derivative biosynthetic process
DNA modification
response to salicylic acid
response to selenium ion
response to organic cyclic compound
dichloromethane metabolic process
response to vitamin E
response to drug
oxidation-reduction process
