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GTF2H1 Antibody (PA5-29379) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of GTF2H1 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: GTF2H1 Polyclonal Antibody (Product # PA5-29379) diluted at 1:500. Red: phalloidin, a cytoskeleton marker. Scale bar = 10 µm.
产品信息
PA5-29379
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 313 of Human GTF2H1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546855
产品详细信息
Recommended positive controls: A549, HeLa, HepG2, HCT116, H1299.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (83%), Xenopus laevis (86%), Chicken (92%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
GTF2H1 (general transcription factor IIH, polypeptide 1, 62kDa) is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA. When complexed to CAK, GTF2H1 is involved in RNA transcription by RNA polymerase II.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Basic transcription factor 2 62 kDa subunit; BTF 2; BTF2 p62; BTF2. TFIIH; General transcription factor IIH polypeptide 1; General transcription factor IIH subunit 1; general transcription factor IIH, polypeptide 1, 62kDa; TF2H1; TFIIH basal transcription factor complex p62 subunit
基因别名: BTF2; GTF2H1; P62; TFB1; TFIIH
UniProt ID: (Human) Q6I9Y7
Entrez Gene ID: (Human) 2965
regulation of cyclin-dependent protein serine/threonine kinase activity
nucleotide-excision repair, DNA duplex unwinding
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
protein phosphorylation
nucleotide-excision repair, DNA incision
positive regulation of transcription from RNA polymerase II promoter
global genome nucleotide-excision repair
