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产品信息
H00002979-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
5E7
抗原
GUCA1B (NP_002089, 93 a.a. approximately 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: KLKWTFKIYD KDGNGCIDRL ELLNIVEGIY QLKKACRREL QTEQDQLLTP EEVVDRIFLL VDENGDGQLS LNEFVEGARR DKWVMKMLQM DMNPSSWLAQ QRRKSAMF
靶标信息
Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin superfamily. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP-1 and GCAP-2. It has been demonstrated that both GCAP-1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP-1 is predominantly localized in the photoreceptor outer segments, while GCAP-2 is found in retina samples.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686E1183; GCAP 2; Guanylate cyclase activator 1B; guanylate cyclase activator 1B (retina); guanylate cyclase-activating protein, photoreceptor 2; Guanylin 2; Guanylyl cyclase-activating protein 2; GUCA 2
基因别名: GCAP2; GUCA1B; GUCA2; RP48
UniProt ID: (Human) Q9UMX6
Entrez Gene ID: (Human) 2979
