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GluR4 Antibody (PA5-142365) in WB
Western Blot analysis of GluR4 in Human Brain lysate (35 µg protein in RIPA buffer) using GluR4 Polyclonal Antibody, Biotin (Product # PA5-142365) at 0.3 µg/mL incubated for 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP blocker as a substitute for skimmed milk.
产品信息
PA5-142365
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence CKKLDQREYPGSETP.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2933015
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
靶标信息
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AMPA-selective glutamate receptor 4; GluR-4; GluR-D; glutamate receptor; Glutamate receptor 4; Glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4
基因别名: GluA4; GLUR4; GLUR4C; GLURD; GRIA4
UniProt ID: (Human) P48058
Entrez Gene ID: (Human) 2893
