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产品信息
PA5-28833
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 855 and 919 of Human GluR 7
偶联物
Unconjugated
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2546309
产品详细信息
Recommended positive controls: NT2D1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); EAA5; Excitatory amino acid receptor 5; GluK3; GluR-7; glutamate receptor; Glutamate receptor 7; Glutamate receptor ionotropic, kainate 3; glutamate receptor, ionotropic, kainate 3
基因别名: EAA5; GLR7; GluK3; GLUR7; GluR7a; GRIK3
UniProt ID: (Human) Q13003
Entrez Gene ID: (Human) 2899
adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
G-protein coupled receptor binding
ionotropic glutamate receptor activity
extracellular-glutamate-gated ion channel activity
glutamate receptor activity
ligand-gated ion channel activity
kainate selective glutamate receptor activity
transmembrane signal receptor
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
regulation of membrane potential
negative regulation of synaptic transmission, glutamatergic
