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GlyT1 (SLC6A9) (extracellular) Antibody (AGT-011-200UL) in WB
Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and human U87-MG glioma cell (lanes 3 and 6) lysates: - 1-3. Anti-GlyT1 (SLC6A9) (extracellular) Antibody (#AGT-011), (1:200).4-6. Anti-GlyT1 (SLC6A9) (extracellular) Antibody , preincubated with GlyT1/SLC6A9 (extracellular) Blocking Peptide (#BLP-GT011).
产品信息
AGT-011-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)RLYVLKLSDDIGD, corresponding to amino acid residues 202-214 of rat GlyT1, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Slc6a9 is a glycine transporter (GlyTs) that belong to a family of high affinity Na+- and Cl-dependent neurotransmitter transporters proteins. There are two subtypes of glycine transporters; GlyT1 (Slc6a9) and GlyT2. Slc6a9 are predominantly located on glia within caudal brain areas. The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by the Slc6a9 gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. Diseases associated with SLC6A9 include Glycine Encephalopathy With Normal Serum Glycine and Infantile Glycine Encephalopathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glycine transporter 1; glycine transporter variant 1a; GlyT-1; Sodium- and chloride-dependent glycine transporter 1; solute carrier family 6 (neurotransmitter transporter, glycine), member 9; Solute carrier family 6 member 9
基因别名: GLYT-1; GLYT-1b; GLYT1; SLC6A9
UniProt ID: (Human) P48067, (Mouse) P28571, (Rat) P28572
Entrez Gene ID: (Human) 6536, (Mouse) 14664, (Rat) 116509
