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Growth Hormone Receptor Antibody (PA5-47094) in Neu
Neutralization of Growth Hormone Receptor in Nb2‚11 rat lymphoma cell line. Samples were incubated in Growth Hormone Receptor polyclonal antibody (Product # PA5-47094). Recombinant Human Growth Hormone R/GHR Fc Chimera inhibits Recombinant Human Growth Hormone induced proliferation in the Nb2‚11 rat lymphoma cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Human Growth Hormone (... View More
产品信息
PA5-47094
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human Growth Hormone R/GHR Ala27-Tyr264
偶联物
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609512
产品详细信息
In direct ELISAs, less than 10% cross-reactivity with recombinant mouse GHR and recombinant rat GHR is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
may play a role in chondrocyte differentiation and positive regulation of longitudinal bond growth and.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GH receptor; growth hormone binding protein; Growth hormone receptor; MGC124963; MGC156665; serum binding protein; Somatotropin receptor
基因别名: GHBP; GHIP; GHR
UniProt ID: (Human) P10912
Entrez Gene ID: (Human) 2690
activation of MAPK activity
allantoin metabolic process
citrate metabolic process
2-oxoglutarate metabolic process
succinate metabolic process
oxaloacetate metabolic process
isoleucine metabolic process
valine metabolic process
creatine metabolic process
fatty acid metabolic process
endocytosis
JAK-STAT cascade
cytokine-mediated signaling pathway
taurine metabolic process
cellular response to hormone stimulus
regulation of multicellular organism growth
positive regulation of multicellular organism growth
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
activation of JAK2 kinase activity
multicellular organism metabolic process
creatinine metabolic process
insulin-like growth factor receptor signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
growth hormone receptor signaling pathway
JAK-STAT cascade involved in growth hormone signaling pathway
