Product References
The phosphorylation of PHF5A by TrkA-ERK1/2-ABL1 cascade regulates centrosome separation.
Cell death & disease
Song C,Zhang Y,Li Y,Bie J,Wang Z,Yang X,Li H,Zhu L,Zhang T,Chang Q,Luo J
26183 was used in Immunoprecipitation to demonstrate that phosphorylation of PHF5A at Y36 by the TrkA-ERK1/2-ABL1 cascade plays a critical role in regulating centrosome separation.
Thu Feb 09 00:00:00 EST 2023
CPEB1-dependent disruption of the mRNA translation program in oocytes during maternal aging.
Nature communications
Takahashi N,Franciosi F,Daldello EM,Luong XG,Althoff P,Wang X,Conti M
26183 was used in Immunoprecipitation to demonstrate that a dysfunction in the oocyte translation program is associated with the decline in oocyte quality during aging.
Thu Jan 26 00:00:00 EST 2023
Genetically encoded chemical crosslinking of RNA in vivo.
Nature chemistry
Sun W,Wang N,Liu H,Yu B,Jin L,Ren X,Shen Y,Wang L
26183 was used in RNA Immunoprecipitation to identify protein-RNA interactions with nucleotide and amino acid specificity, such as identifying target RNAs for the RNA chaperone Hfq in Escherichia coli and pinpointing N6-methyladenosine on RNA with single-nucleotide resolution throughout the transcriptome.
Sun Jan 01 00:00:00 EST 2023
Evolution of nanobodies specific for BCL11A.
Proceedings of the National Academy of Sciences of the United States of America
Yin M,Izadi M,Tenglin K,Viennet T,Zhai L,Zheng G,Arthanari H,Dassama LMK,Orkin SH
26183 was used in Western Blotting to describe the optimization of nanobodies specific for BCL11A, a validated target for the treatment of hemoglobin disorders.
Tue Jan 17 00:00:00 EST 2023
Multiple phosphorylation of the Cdc48/p97 cofactor protein Shp1/p47 occurs upon cell stress in budding yeast.
Life science alliance
Agrotis A,Lamoliatte F,Williams TD,Black A,Horberry R,Rousseau A
26183 was used in Western Blotting to identify a phosphoregulation of Shp1 at multiple sites by Mpk1 kinase and PP1 phosphatase upon various stresses.
Sat Apr 01 00:00:00 EDT 2023
Harnessing Split-Inteins as a Tool for the Selective Modification of Surface Receptors in Live Cells.
Chembiochem : a European journal of chemical biology
Ray DM,Flood JR,David Y
26183 was used in Immunocytochemistry, Immunoprecipitation, Western Blot to study intein biorthogonality to mammalian systems, site specificity, fast kinetics, and auto-processing nature as an attractive option for modifying surface proteins.
Wed Feb 01 00:00:00 EST 2023
Major Vault Protein Prevents Atherosclerotic Plaque Destabilization by Suppressing Macrophage ASK1-JNK Signaling.
Arteriosclerosis, thrombosis, and vascular biology
Liu Q,Pan J,Bao L,Xu C,Qi Y,Jiang B,Wang D,Zhu X,Li X,Zhang H,Bai H,Yang Q,Ma J,Wiemer EAC,Ben J,Chen Q
26183 was used in Western Blotting to support that MVP may act as an inhibitor for ASK1-JNK signaling-mediated MMP-9 production in macrophages and, thereby, attenuate unstable plaque formation.
Sun May 01 00:00:00 EDT 2022
MG53 Inhibits Necroptosis Through Ubiquitination-Dependent RIPK1 Degradation for Cardiac Protection Following Ischemia/Reperfusion Injury.
Frontiers in cardiovascular medicine
Wang Q,Park KH,Geng B,Chen P,Yang C,Jiang Q,Yi F,Tan T,Zhou X,Bian Z,Ma J,Zhu H
26183 was used in Immunoprecipitation to provide a molecular mechanism of a potential beneficial role of ROS following acute myocardial infarction. Thus, fine-tuning ROS levels might be critical for cardioprotection.
Sat Jul 16 00:00:00 EDT 2022
Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.
International journal of biological sciences
Wang T,Lu Z,Han T,Wang Y,Gan M,Wang JB
Published figure using HA Tag monoclonal antibody (Product # 26183) in Immunoprecipitation
Mon Jul 25 00:00:00 EDT 2022
Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.
International journal of biological sciences
Wang T,Lu Z,Han T,Wang Y,Gan M,Wang JB
Published figure using HA Tag monoclonal antibody (Product # 26183) in Immunoprecipitation
Mon Jul 25 00:00:00 EDT 2022
Structural and functional analysis of the roles of influenza C virus membrane proteins in assembly and budding.
The Journal of biological chemistry
Zhang X,Abel T,Su S,Herrmann A,Ludwig K,Veit M
Published figure using HA Tag monoclonal antibody (Product # 26183) in Immunocytochemistry
Tue Mar 01 00:00:00 EST 2022
Structural and functional analysis of the roles of influenza C virus membrane proteins in assembly and budding.
The Journal of biological chemistry
Zhang X,Abel T,Su S,Herrmann A,Ludwig K,Veit M
Published figure using HA Tag monoclonal antibody (Product # 26183) in Immunocytochemistry
Tue Mar 01 00:00:00 EST 2022
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Cell death & disease
Wang Y,Lei J,Zhang S,Wang X,Jin J,Liu Y,Gan M,Yuan Y,Sun L,Li X,Han T,Wang JB
26183 was used in Western Blotting to highlight a novel mechanism for 4EBP1 as a new cellular glucose sensor in regulating cancer cell death under glucose deprivation conditions, which was different from its classical function as a translational repressor.
Tue Dec 27 00:00:00 EST 2022
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Cell death & disease
Wang Y,Lei J,Zhang S,Wang X,Jin J,Liu Y,Gan M,Yuan Y,Sun L,Li X,Han T,Wang JB
26183 was used in Western Blotting to highlight a novel mechanism for 4EBP1 as a new cellular glucose sensor in regulating cancer cell death under glucose deprivation conditions, which was different from its classical function as a translational repressor.
Tue Dec 27 00:00:00 EST 2022
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Cell death & disease
Wang Y,Lei J,Zhang S,Wang X,Jin J,Liu Y,Gan M,Yuan Y,Sun L,Li X,Han T,Wang JB
26183 was used in Western Blotting to highlight a novel mechanism for 4EBP1 as a new cellular glucose sensor in regulating cancer cell death under glucose deprivation conditions, which was different from its classical function as a translational repressor.
Tue Dec 27 00:00:00 EST 2022
PROBER identifies proteins associated with programmable sequence-specific DNA in living cells.
Nature methods
Mondal S,Ramanathan M,Miao W,Meyers RM,Rao D,Lopez-Pajares V,Siprashvili Z,Reynolds DL,Porter DF,Ferguson I,Neela P,Zhao Y,Meservey LM,Guo M,Yang YY,Li L,Wang Y,Khavari PA
26183 was used in Immunocytochemistry to develop proximal biotinylation by episomal recruitment (PROBER).
Mon Aug 01 00:00:00 EDT 2022
The envelope proteins from SARS-CoV-2 and SARS-CoV potently reduce the infectivity of human immunodeficiency virus type 1 (HIV-1).
Retrovirology
Henke W,Waisner H,Arachchige SP,Kalamvoki M,Stephens E
26183 was used in Immunoprecipitation to indicate that while viroporins from homologous viruses can enhance virus release, show that a viroporin from a heterologous virus can suppress HIV-1 protein synthesis and release of infectious virus.
Sat Nov 19 00:00:00 EST 2022
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Autophagy
Han T,Wang P,Wang Y,Xun W,Lei J,Wang T,Lu Z,Gan M,Zhang W,Yu B,Wang JB
26183 was used in Cell growth assay to discover new functions of FAIM and elucidated an important molecular mechanism for GAC in maintaining its high enzymatic activity and protein stability.
Wed Jun 01 00:00:00 EDT 2022
Incorporation of fucose into glycans independent of the GDP-fucose transporter SLC35C1 preferentially utilizes salvaged over de novo GDP-fucose.
The Journal of biological chemistry
Skurska E,Szulc B,Maszczak-Seneczko D,Wiktor M,Wiertelak W,Makowiecka A,Olczak M
26183 was used in Immunocytochemistry, Immunoprecipitation, Western Blot to imply that the Golgi systems of GDP-fucose transport discriminate between substrate pools obtained from different metabolic pathways, which suggests a functional connection between nucleotide sugar transporters and nucleotide sugar synthases.
Mon Aug 01 00:00:00 EDT 2022
MTG8 interacts with LHX6 to specify cortical interneuron subtype identity.
Nature communications
Asgarian Z,Oliveira MG,Stryjewska A,Maragkos I,Rubin AN,Magno L,Pachnis V,Ghorbani M,Hiebert SW,Denaxa M,Kessaris N
26183 was used in Western Blot, Immunoprecipitation to study the role of transcriptional co-factors and modifiers in specification of cortical interneuron subtype identity.
Mon Sep 05 00:00:00 EDT 2022
MTG8 interacts with LHX6 to specify cortical interneuron subtype identity.
Nature communications
Asgarian Z,Oliveira MG,Stryjewska A,Maragkos I,Rubin AN,Magno L,Pachnis V,Ghorbani M,Hiebert SW,Denaxa M,Kessaris N
26183 was used in Western Blot, Immunoprecipitation to study the role of transcriptional co-factors and modifiers in specification of cortical interneuron subtype identity.
Mon Sep 05 00:00:00 EDT 2022
The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes.
PloS one
Porcellato E,González-Sánchez JC,Ahlmann-Eltze C,Elsakka MA,Shapira I,Fritsch J,Navarro JA,Anders S,Russell RB,Wieland FT,Metzendorf C
26183 was used in Western Blotting to present the palmitoylome of Drosophila S2R+ cells, comprising 198 proteins, an estimated 3.5% of expressed genes in these cells.
Tue Aug 16 00:00:00 EDT 2022
Human Respiratory Syncytial Virus NS2 Protein Induces Autophagy by Modulating Beclin1 Protein Stabilization and ISGylation.
mBio
Chiok K,Pokharel SM,Mohanty I,Miller LG,Gao SJ,Haas AL,Tran KC,Teng MN,Bose S
26183 was used in Western Blot, Immunocytochemistry to study activation of autophagy by respiratory syncytial virus NS2 protein.
Tue Feb 22 00:00:00 EST 2022
Human Respiratory Syncytial Virus NS2 Protein Induces Autophagy by Modulating Beclin1 Protein Stabilization and ISGylation.
mBio
Chiok K,Pokharel SM,Mohanty I,Miller LG,Gao SJ,Haas AL,Tran KC,Teng MN,Bose S
26183 was used in Western Blot, Immunocytochemistry to study activation of autophagy by respiratory syncytial virus NS2 protein.
Tue Feb 22 00:00:00 EST 2022
Immunity functions of Arabidopsis pathogenesis-related 1 are coupled but not confined to its C-terminus processing and trafficking.
Molecular plant pathology
Pečenková T,Pejchar P,Moravec T,Drs M,Haluška S,Šantrůček J,Potocká A,Žárský V,Potocký M
26183 was used in Western Blotting to find that en route from the endoplasmic reticulum, the PR1 protein transits via the multivesicular body and undergoes partial proteolytic processing, dependent on an intact C-terminal motif.
Sun May 01 00:00:00 EDT 2022
Physical and functional interactome atlas of human receptor tyrosine kinases.
EMBO reports
Salokas K,Liu X,Öhman T,Chowdhury I,Gawriyski L,Keskitalo S,Varjosalo M
26183 was used in Immunocytochemistry-immunofluorescence to apply three complementary methods to map the molecular context and substrate profiles of RTKs.
Tue Jun 07 00:00:00 EDT 2022
MAGED2 Is Required under Hypoxia for cAMP Signaling by Inhibiting MDM2-Dependent Endocytosis of G-Alpha-S.
Cells
Seaayfan E,Nasrah S,Quell L,Kleim M,Weber S,Meyer H,Laghmani K,Kömhoff M
26183 was used in Immunocytochemistry-immunofluorescence to reveal that MAGED2 is essential for the cAMP/PKA pathway under hypoxia to specifically regulate Gαs endocytosis by blocking MDM2-dependent ubiquitination of Gαs.
Tue Aug 16 00:00:00 EDT 2022
Duck TRIM29 negatively regulates type I IFN production by targeting MAVS.
Frontiers in immunology
Li W,Song Y,Du Y,Huang Z,Zhang M,Chen Z,He Z,Ding Y,Zhang J,Zhao L,Sun H,Jiao P
26183 was used in Western blotting following immunoprecipitation to demonstrate that duTRIM29 negatively regulates type I IFN production by targeting duMAVS in ducks.
Tue Jan 24 00:00:00 EST 2023
Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.
PLoS genetics
Gurtan A,Dominy J,Khalid S,Vong L,Caplan S,Currie T,Richards S,Lamarche L,Denning D,Shpektor D,Gurinovich A,Rasheed A,Hameed S,Saeed S,Saleem I,Jalal A,Abbas S,Sultana R,Rasheed SZ,Memon FU,Shah N,Ishaq M,Khera AV,Danesh J,Frossard P,Saleheen D
26183 was used in Western Blot to indicate that GPR151 antagonism is not a compelling therapeutic approach to treatment of obesity.
Fri Apr 01 00:00:00 EDT 2022
High-resolution map of plastid-encoded RNA polymerase binding patterns demonstrates a major role of transcription in chloroplast gene expression.
The Plant journal : for cell and molecular biology
Palomar VM,Jaksich S,Fujii S,Kuciński J,Wierzbicki AT
26183 was used in Immunocytochemistry, Immunoprecipitation, Western Blot, ChIP Assay to establish highlighy specific approach using ptChIP-seq which detected and demonstrated impact of PEP on cholrorplast gene expression.
Mon Aug 01 00:00:00 EDT 2022
Overexpression of Wild-Type ACVR1 in Fibrodysplasia Ossificans Progressiva Mice Rescues Perinatal Lethality and Inhibits Heterotopic Ossification.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Yamamoto M,Stoessel SJ,Yamamoto S,Goldhamer DJ
26183 was used in Western Blotting to investigate the impact of overexpressing human wild-type ACVR1 in a genetic mouse model of Fibrodysplasia Ossificans Progressiva (FOP).
Tue Nov 01 00:00:00 EDT 2022
GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia.
International journal of molecular sciences
Marwarha G,Røsand Ø,Slagsvold KH,Høydal MA
26183 was used in Western Blotting to unveil that the inhibition of GSK3β kinase activity is indispensable in mediating the miR-210-orchestrated protective cellular response to hypoxia-induced apoptotic cell death.
Fri Aug 19 00:00:00 EDT 2022
Chicken telomerase reverse transcriptase mediates LMH cell pyroptosis by regulating the nuclear factor-kappa B signaling pathway.
Poultry science
Xiang Y,Yu Y,Li Q,Chen J,Li Y,Cao W
26183 was used in Western Blotting to find that chTERT upregulated the expression of p65 and p50, downregulated the expression of IκBα, promoted the phosphorylation of p65, p50, and IκBα, and significantly increased the transcript levels of the inflammatory cytokines IFNγ, TNFα, and IL-6 in LMH cells.
Wed Jun 01 00:00:00 EDT 2022
Reconstitution System of NLRP3 Inflammasome in HEK293T Cells.
Methods in molecular biology (Clifton, N.J.)
Chen S,Chi Z,Wang D
26183 was used in Western Blotting to describe a comprehensive guide to study NLRP3 inflammasome activation in HEK293T cell reconstitution system, which could provide direct biochemical evidence in protein interaction and posttranslational modification of the complex.
Tue Mar 01 00:00:00 EST 2022
CK1α upregulates the IFNAR1 expression to prompt the anti-HBV effect of type I IFN in hepatoma carcinoma cells.
Virologica Sinica
Xiong J,Jiang Y,Zhang J,Chen Y,Hu Y
26183 was used in Western Blotting to provide evidence that CK1α positively regulates the anti-HBV activity of IFN-α in hepatoma carcinoma cells, which would be a promising therapeutic target to improve the effectiveness of IFN-α therapy to cure CHB.
Thu Dec 01 00:00:00 EST 2022
SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport.
Developmental cell
Yan R,Chen K,Wang B,Xu K
26183 was used in Western Blot to report a highly elongated tubular ER-Golgi intermediate compartment (t-ERGIC) that selectively expedites the ER-to-Golgi transport for soluble cargoes of the receptor SURF4.
Mon Feb 28 00:00:00 EST 2022
A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation.
Immunity
Liu Z,Nailwal H,Rector J,Rahman MM,Sam R,McFadden G,Chan FK
26183 was used in Flow Cytometry to identify a viral inhibitor that binds to the host SKP1-Cullin1-F-box (SCF) machinery and the essential necroptosis kinase receptor interacting protein kinase 3 (RIPK3).
Tue Feb 09 00:00:00 EST 2021
Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Nature chemical biology
Wellner A,McMahon C,Gilman MSA,Clements JR,Clark S,Nguyen KM,Ho MH,Hu VJ,Shin JE,Feldman J,Hauser BM,Caradonna TM,Wingler LM,Schmidt AG,Marks DS,Abraham J,Kruse AC,Liu CC
26183 was used in Flow Cytometry to develop the autonomous hypermutation yeast surface display technique for recombinant antibody generation.
Fri Oct 01 00:00:00 EDT 2021
Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model.
Proceedings of the National Academy of Sciences of the United States of America
Maeda DLNF,Tian D,Yu H,Dar N,Rajasekaran V,Meng S,Mahsoub HM,Sooryanarain H,Wang B,Heffron CL,Hassebroek A,LeRoith T,Meng XJ,Zeichner SL
26183 was used in Flow cytometry/Cell sorting to demonstrate that both PEDV FP and SARS-CoV-2 FP vaccines induced potent anamnestic responses upon virus challenge, potentiated interferon-γ responses, reduced viral RNA loads in jejunum tissue, and provided significant protection against clinical disease.
Tue May 04 00:00:00 EDT 2021
Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model.
Proceedings of the National Academy of Sciences of the United States of America
Maeda DLNF,Tian D,Yu H,Dar N,Rajasekaran V,Meng S,Mahsoub HM,Sooryanarain H,Wang B,Heffron CL,Hassebroek A,LeRoith T,Meng XJ,Zeichner SL
26183 was used in Flow cytometry/Cell sorting to demonstrate that both PEDV FP and SARS-CoV-2 FP vaccines induced potent anamnestic responses upon virus challenge, potentiated interferon-γ responses, reduced viral RNA loads in jejunum tissue, and provided significant protection against clinical disease.
Tue May 04 00:00:00 EDT 2021
SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition.
Biosensors & bioelectronics
Azad T,Singaravelu R,Fekete EEF,Taha Z,Rezaei R,Arulanandam R,Boulton S,Diallo JS,Ilkow CS,Bell JC
26183 was used in Western Blotting to develop a novel bioluminescence-based biosensor to probe a key host-virus interaction during viral entry.
Sat May 15 00:00:00 EDT 2021
Adaptability of the ubiquitin-proteasome system to proteolytic and folding stressors.
The Journal of cell biology
Work JJ,Brandman O
26183 was used in Western Blotting to reveal the distinct effects of proteotoxic stressors and the versatility of cells in adapting the UPS.
Mon Mar 01 00:00:00 EST 2021
Adaptability of the ubiquitin-proteasome system to proteolytic and folding stressors.
The Journal of cell biology
Work JJ,Brandman O
26183 was used in Western Blotting to reveal the distinct effects of proteotoxic stressors and the versatility of cells in adapting the UPS.
Mon Mar 01 00:00:00 EST 2021
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
The Journal of cell biology
Oshima Y,Cartier E,Boyman L,Verhoeven N,Polster BM,Huang W,Kane M,Lederer WJ,Karbowski M
26183 was used in Immunocytochemistry, Western Blot to report that acute reduction in mitochondrial translation fidelity causes ubiquitination of the inner mitochondrial membrane proteins.
Mon Jun 07 00:00:00 EDT 2021
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
The Journal of cell biology
Oshima Y,Cartier E,Boyman L,Verhoeven N,Polster BM,Huang W,Kane M,Lederer WJ,Karbowski M
26183 was used in Immunocytochemistry, Western Blot to report that acute reduction in mitochondrial translation fidelity causes ubiquitination of the inner mitochondrial membrane proteins.
Mon Jun 07 00:00:00 EDT 2021
Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength.
Development (Cambridge, England)
Kong JH,Young CB,Pusapati GV,Espinoza FH,Patel CB,Beckert F,Ho S,Patel BB,Gabriel GC,Aravind L,Bazan JF,Gunn TM,Lo CW,Rohatgi R
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Fri Oct 01 00:00:00 EDT 2021
A Valsa mali Effector Protein 1 Targets Apple (Malus domestica) Pathogenesis-Related 10 Protein to Promote Virulence.
Frontiers in plant science
Wang W,Nie J,Lv L,Gong W,Wang S,Yang M,Xu L,Li M,Du H,Huang L
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Tue Oct 26 00:00:00 EDT 2021
Inhibitors of Coronavirus 3CL Proteases Protect Cells from Protease-Mediated Cytotoxicity.
Journal of virology
Resnick SJ,Iketani S,Hong SJ,Zask A,Liu H,Kim S,Melore S,Lin FY,Nair MS,Huang Y,Lee S,Tay NES,Rovis T,Yang HW,Xing L,Stockwell BR,Ho DD,Chavez A
26183 was used in Western Blot to describe a mammalian cell-based assay to identify coronavirus 3CL protease (3CLpro) inhibitors.
Thu Jun 24 00:00:00 EDT 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV)-host interactome screen identifies viral nucleoprotein-associated host factors as potential antiviral targets.
Computational and structural biotechnology journal
Cao J,Lu G,Wen L,Luo P,Huang Y,Liang R,Tang K,Qin Z,Chan CC,Chik KK,Du J,Yin F,Ye ZW,Chu H,Jin DY,Yuen KY,Chan JF,Yuan S
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Sat Oct 30 00:00:00 EDT 2021
A novel role of ADGRF1 (GPR110) in promoting cellular quiescence and chemoresistance in human epidermal growth factor receptor 2-positive breast cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Abdulkareem NM,Bhat R,Qin L,Vasaikar S,Gopinathan A,Mitchell T,Shea MJ,Nanda S,Thangavel H,Zhang B,De Angelis C,Schiff R,Trivedi MV
26183 was used in Western Blotting to evaluate the effects of ADGRF1 overexpression on tumorigenesis and signaling pathways using two human epidermal growth factor receptor-2-positive (HER2+) breast cancer (BC) cell-line models.
Thu Jul 01 00:00:00 EDT 2021
RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons.
Molecular and cellular biology
Xiang C,Frietze KK,Bi Y,Li Y,Dal Pozzo V,Pal S,Alexander N,Baubet V,D'Acunto V,Mason CE,Davuluri RV,Dahmane N
26183 was used in Immunoprecipitation to conclude that RP58 acts as an in vivo master guardian of the neuronal identity transcriptome, and its function may be required to prevent brain disease development, including glioma progression.
Wed Jun 23 00:00:00 EDT 2021
Crosstalk between phosphorylation and ubiquitination is involved in high salt-induced WNK4 expression.
Experimental and therapeutic medicine
Zhao X,Lai G,Tu J,Liu S,Zhao Y
26183 was used in Western Blot, Immunoprecipitation to study how salt regulates the serine/threonine kinase 'with no lysine 4' (WNK4) in C57BL/6 mice and HEK293 cells.
Mon Feb 01 00:00:00 EST 2021
Crosstalk between phosphorylation and ubiquitination is involved in high salt-induced WNK4 expression.
Experimental and therapeutic medicine
Zhao X,Lai G,Tu J,Liu S,Zhao Y
26183 was used in Western Blot, Immunoprecipitation to study how salt regulates the serine/threonine kinase 'with no lysine 4' (WNK4) in C57BL/6 mice and HEK293 cells.
Mon Feb 01 00:00:00 EST 2021
TRIM21 inhibits porcine epidemic diarrhea virus proliferation by proteasomal degradation of the nucleocapsid protein.
Archives of virology
Wang H,Chen X,Kong N,Jiao Y,Sun D,Dong S,Qin W,Zhai H,Yu L,Zheng H,Tong W,Yu H,Tong G,Shan T
26183 was used in Immunocytochemistry, Western Blot to provide information about the role of TRIM21 in PEDV proliferation and increase our understanding of host-virus interactions.
Thu Jul 01 00:00:00 EDT 2021
TRIM21 inhibits porcine epidemic diarrhea virus proliferation by proteasomal degradation of the nucleocapsid protein.
Archives of virology
Wang H,Chen X,Kong N,Jiao Y,Sun D,Dong S,Qin W,Zhai H,Yu L,Zheng H,Tong W,Yu H,Tong G,Shan T
26183 was used in Immunocytochemistry, Western Blot to provide information about the role of TRIM21 in PEDV proliferation and increase our understanding of host-virus interactions.
Thu Jul 01 00:00:00 EDT 2021
Zinc transporter mutations linked to acrodermatitis enteropathica disrupt function and cause mistrafficking.
The Journal of biological chemistry
Kuliyev E,Zhang C,Sui D,Hu J
Published figure using HA Tag monoclonal antibody (Product # 26183) in Immunocytochemistry
Wed Aug 25 00:00:00 EDT 2021
Crosstalk between Brassinosteroid and Redox Signaling Contributes to the Activation of CBF Expression during Cold Responses in Tomato.
Antioxidants (Basel, Switzerland)
Fang P,Wang Y,Wang M,Wang F,Chi C,Zhou Y,Zhou J,Shi K,Xia X,Foyer CH,Yu J
Published figure using HA Tag monoclonal antibody (Product # 26183) in ChIP assay
Thu Mar 25 00:00:00 EDT 2021
Translocation of TMEM175 Lysosomal Potassium Channel to the Plasma Membrane by Dynasore Compounds.
International journal of molecular sciences
Pergel E,Veres I,Csigi GI,Czirják G
26183 was used in Western Blot to show that the expression of mouse TMEM175 results in very small K+ currents through the plasma membrane in Xenopus laevis oocytes.
Wed Sep 29 00:00:00 EDT 2021
Translocation of TMEM175 Lysosomal Potassium Channel to the Plasma Membrane by Dynasore Compounds.
International journal of molecular sciences
Pergel E,Veres I,Csigi GI,Czirják G
26183 was used in Western Blot to show that the expression of mouse TMEM175 results in very small K+ currents through the plasma membrane in Xenopus laevis oocytes.
Wed Sep 29 00:00:00 EDT 2021
Dnj1 Promotes Virulence in Cryptococcus neoformans by Maintaining Robust Endoplasmic Reticulum Homeostasis Under Temperature Stress.
Frontiers in microbiology
Horianopoulos LC,Lee CWJ,Hu G,Caza M,Kronstad JW
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Wed Sep 29 00:00:00 EDT 2021
Dnj1 Promotes Virulence in Cryptococcus neoformans by Maintaining Robust Endoplasmic Reticulum Homeostasis Under Temperature Stress.
Frontiers in microbiology
Horianopoulos LC,Lee CWJ,Hu G,Caza M,Kronstad JW
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Wed Sep 29 00:00:00 EDT 2021
Genetic Code Expansion and Click-Chemistry Labeling to Visualize GABA-A Receptors by Super-Resolution Microscopy.
Frontiers in synaptic neuroscience
Kuhlemann A,Beliu G,Janzen D,Petrini EM,Taban D,Helmerich DA,Doose S,Bruno M,Barberis A,Villmann C,Sauer M,Werner C
26183 was used in Immunocytochemistry, Immunoprecipitation, Western Blot, Sample Prep to report site-specific labeling of the extracellular domain of γ-aminobutyric acid type A (GABA-A) receptor subunits by genetic code expansion (GCE) with unnatural amino acids (ncAA) combined with bioorthogonal click-chemistry labeling with tetrazine dyes in HEK-293-T cells and primary cultured neurons.
Wed Dec 15 00:00:00 EST 2021
African Swine Fever Virus E120R Protein Inhibits Interferon Beta Production by Interacting with IRF3 To Block Its Activation.
Journal of virology
Liu H,Zhu Z,Feng T,Ma Z,Xue Q,Wu P,Li P,Li S,Yang F,Cao W,Xue Z,Chen H,Liu X,Zheng H
26183 was used in Western Blotting to explore a novel antagonistic mechanism of ASFV, which is critical for guiding the development of ASFV live-attenuated vaccines.
Wed Aug 25 00:00:00 EDT 2021
Identification of Nucleolin as a Novel AEG-1-Interacting Protein in Breast Cancer via Interactome Profiling.
Cancers
Lee SJ,Choi KM,Bang G,Park SG,Kim EB,Choi JW,Chung YH,Kim J,Lee SG,Kim E,Kim JY
26183 was used in Immunoprecipitation, Western Blot to identify NCL as a novel mediator of the oncogenic function of AEG-1, and suggest that c-Met could be associated with the oncogenic function of the AEG-1-NCL complex in the context of breast cancer.
Mon Jun 07 00:00:00 EDT 2021
Identification of Nucleolin as a Novel AEG-1-Interacting Protein in Breast Cancer via Interactome Profiling.
Cancers
Lee SJ,Choi KM,Bang G,Park SG,Kim EB,Choi JW,Chung YH,Kim J,Lee SG,Kim E,Kim JY
26183 was used in Immunoprecipitation, Western Blot to identify NCL as a novel mediator of the oncogenic function of AEG-1, and suggest that c-Met could be associated with the oncogenic function of the AEG-1-NCL complex in the context of breast cancer.
Mon Jun 07 00:00:00 EDT 2021
T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling.
The Journal of clinical investigation
Marchelletta RR,Krishnan M,Spalinger MR,Placone TW,Alvarez R,Sayoc-Becerra A,Canale V,Shawki A,Park YS,Bernts LH,Myers S,Tremblay ML,Barrett KE,Krystofiak E,Kachar B,McGovern DP,Weber CR,Hanson EM,Eckmann L,McCole DF
26183 was used in Western Blotting to demonstrate that TCPTP protected against intestinal barrier dysfunction induced by the inflammatory cytokine IFN-γ by 2 mechanisms: it maintained localization of zonula occludens 1 and occludin at apical tight junctions and restricted both expression and insertion of the cation pore-forming transmembrane protein, claudin-2, at tight junctions through upregulation of the inhibitory cysteine protease, matriptase.
Wed Sep 01 00:00:00 EDT 2021
δ-Protocadherins regulate neural progenitor cell division by antagonizing Ryk and Wnt/β-catenin signaling.
iScience
Biswas S,Emond MR,Chenoweth KP,Jontes JD
26183 was used in Immunocytochemistry, Immunoprecipitation, Western Blot, Sample Prep to find that δ-protocadherins are novel regulators of Wnt/β-catenin signaling that may control the development of neural circuits by defining a molecular code for the identity of neural progenitor cells and differentially regulating their proliferation.
Fri Aug 20 00:00:00 EDT 2021
UBE2S promotes cell chemoresistance through PTEN-AKT signaling in hepatocellular carcinoma.
Cell death discovery
Gui L,Zhang S,Xu Y,Zhang H,Zhu Y,Kong L
26183 was used in Western Blot to show ubiquitin-conjugating enzyme E2S (UBE2S) upregulation is relevant with large tumor size, recurrence, and advanced TNM stage, serving as an independent risk factor of overall survival and disease-free survival for hepatocellular cancer patients.
Tue Nov 16 00:00:00 EST 2021
Histone demethylase JMJD2D promotes the self-renewal of liver cancer stem-like cells by enhancing EpCAM and Sox9 expression.
The Journal of biological chemistry
Deng Y,Li M,Zhuo M,Guo P,Chen Q,Mo P,Li W,Yu C
26183 was used in Western Blot to suggest that JMJD2D promotes LCSC self-renewal by enhancing EpCAM and Sox9 expression via Wnt/β-catenin and Notch signaling pathways and is a potential therapeutic target for liver cancer.
Wed Aug 18 00:00:00 EDT 2021
Ablation of CRBN induces loss of type I collagen and SCH in mouse skin by fibroblast senescence via the p38 MAPK pathway.
Aging
Jeon S,Yoon YS,Kim HK,Han J,Lee KM,Seol JE,Cho SK,Park CS
26183 was used in Western Blotting to demonstrate reversion of the decreased protein level of collagen I after the reintroduction of the CRBN gene back into CRBN KO MEFs.
Wed Mar 03 00:00:00 EST 2021
Glycosyltransferase POMGNT1 deficiency strengthens N-cadherin-mediated cell-cell adhesion.
The Journal of biological chemistry
Noor SI,Hoffmann M,Rinis N,Bartels MF,Winterhalter PR,Hoelscher C,Hennig R,Himmelreich N,Thiel C,Ruppert T,Rapp E,Strahl S
26183 was used in Western Blot to indicate that changes in cadherin-mediated cell-cell adhesion and other EMT-related processes may contribute to the complex clinical symptoms of MEB or α-dystroglycanopathy in general and suggests that the impact of changes in O-mannosylation on N-glycosylation has been underestimated.
Mon Aug 30 00:00:00 EDT 2021
A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.
Nature
Mok BY,de Moraes MH,Zeng J,Bosch DE,Kotrys AV,Raguram A,Hsu F,Radey MC,Peterson SB,Mootha VK,Mougous JD,Liu DR
26183 was used in Western Blotting to describe an interbacterial toxin, which we name DddA, that catalyses the deamination of cytidines within dsDNA.
Wed Jul 01 00:00:00 EDT 2020
Molecular Basis of Chemotactile Sensation in Octopus.
Cell
van Giesen L,Kilian PB,Allard CAH,Bellono NW
26183 was used in Western Blot to demonstrate that the peripherally distributed octopus nervous system is a key site for signal processing and highlight how molecular and anatomical features synergistically evolve to suit an animal's environmental context.
Thu Oct 29 00:00:00 EDT 2020
Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2.
Immunity
Ostendorf T,Zillinger T,Andryka K,Schlee-Guimaraes TM,Schmitz S,Marx S,Bayrak K,Linke R,Salgert S,Wegner J,Grasser T,Bauersachs S,Soltesz L,Hübner MP,Nastaly M,Coch C,Kettwig M,Roehl I,Henneke M,Hoerauf A,Barchet W,Gärtner J,Schlee M,Hartmann G,Bartok E
26183 was used in Western Blotting to identify an essential function of RNase T2 and RNase 2 upstream of TLR8 and provide insight into TLR8 activation.
Tue Apr 14 00:00:00 EDT 2020
Functional α6β4 acetylcholine receptor expression enables pharmacological testing of nicotinic agonists with analgesic properties.
The Journal of clinical investigation
Knowland D,Gu S,Eckert WA,Dawe GB,Matta JA,Limberis J,Wickenden AD,Bhattacharya A,Bredt DS
26183 was used in Western Blotting to identify roles for IRE1α and BARP in neurotransmitter receptor assembly and unlock drug discovery for the previously elusive α6β4 receptor.
Mon Nov 02 00:00:00 EST 2020
Structural basis for STAT2 suppression by flavivirus NS5.
Nature structural & molecular biology
Wang B,Thurmond S,Zhou K,Sánchez-Aparicio MT,Fang J,Lu J,Gao L,Ren W,Cui Y,Veit EC,Hong H,Evans MJ,O'Leary SE,García-Sastre A,Zhou ZH,Hai R,Song J
26183 was used in Immunoprecipitation to determine the crystal and cryo electron microscopy structures of Zika virus non-structural protein 5 in complex with human STAT2.
Thu Oct 01 00:00:00 EDT 2020
Crosstalk of PIF4 and DELLA modulates CBF transcript and hormone homeostasis in cold response in tomato.
Plant biotechnology journal
Wang F,Chen X,Dong S,Jiang X,Wang L,Yu J,Zhou Y
26183 was used in Western Blot to reveal that plants integrate light and temperature signals to better adapt to cold stress through shared hormone pathways and transcriptional regulators, which may provide a comprehensive understanding of plant growth and survival in a changing environment.
Wed Apr 01 00:00:00 EDT 2020
Crosstalk of PIF4 and DELLA modulates CBF transcript and hormone homeostasis in cold response in tomato.
Plant biotechnology journal
Wang F,Chen X,Dong S,Jiang X,Wang L,Yu J,Zhou Y
26183 was used in Western Blot to reveal that plants integrate light and temperature signals to better adapt to cold stress through shared hormone pathways and transcriptional regulators, which may provide a comprehensive understanding of plant growth and survival in a changing environment.
Wed Apr 01 00:00:00 EDT 2020
Hair cell α9α10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products.
Proceedings of the National Academy of Sciences of the United States of America
Gu S,Knowland D,Matta JA,O'Carroll ML,Davini WB,Dhara M,Kweon HJ,Bredt DS
26183 was used in Western Blotting to determine that assembly and surface expression of α9α10 require ligand binding.
Tue Sep 29 00:00:00 EDT 2020
Ligand-dependent downregulation of MR1 cell surface expression.
Proceedings of the National Academy of Sciences of the United States of America
Salio M,Awad W,Veerapen N,Gonzalez-Lopez C,Kulicke C,Waithe D,Martens AWJ,Lewinsohn DM,Hobrath JV,Cox LR,Rossjohn J,Besra GS,Cerundolo V
26183 was used in Flow cytometry/Cell sorting to identify one ligand, 3-([2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl]formamido)propanoic acid, DB28, as well as an analog, methyl 3-([2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl]formamido)propanoate, NV18.1, that down-regulate MR1 from the cell surface and retain MR1 molecules in the endoplasmic reticulum (ER) in an immature form.
Tue May 12 00:00:00 EDT 2020
MICOS subcomplexes assemble independently on the mitochondrial inner membrane in proximity to ER contact sites.
The Journal of cell biology
Tirrell PS,Nguyen KN,Luby-Phelps K,Friedman JR
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Mon Nov 02 00:00:00 EST 2020
Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.
The Journal of cell biology
Khalaj AJ,Sterky FH,Sclip A,Schwenk J,Brunger AT,Fakler B,Südhof TC
26183 was used in Affinity chromatography to identify FAM19A/TAFA proteins, "orphan" cytokines, as neurexin regulators that interact with all neurexins, except for neurexin-1γ, via an unusual mechanism.
Mon Sep 07 00:00:00 EDT 2020
Poxvirus-encoded decapping enzymes promote selective translation of viral mRNAs.
PLoS pathogens
Cantu F,Cao S,Hernandez C,Dhungel P,Spradlin J,Yang Z
26183 was used in Western Blot to identify a mechanism by which VACV mRNAs are selectively translated through subverting viral decapping enzymes to stimulate 5'-poly(A) leader-mediated translation.
Thu Oct 01 00:00:00 EDT 2020
Poxvirus-encoded decapping enzymes promote selective translation of viral mRNAs.
PLoS pathogens
Cantu F,Cao S,Hernandez C,Dhungel P,Spradlin J,Yang Z
26183 was used in Western Blot to identify a mechanism by which VACV mRNAs are selectively translated through subverting viral decapping enzymes to stimulate 5'-poly(A) leader-mediated translation.
Thu Oct 01 00:00:00 EDT 2020
Transcriptomic and genetic approaches reveal an essential role of the NAC transcription factor SlNAP1 in the growth and defense response of tomato.
Horticulture research
Wang J,Zheng C,Shao X,Hu Z,Li J,Wang P,Wang A,Yu J,Shi K
Published figure using HA Tag monoclonal antibody (Product # 26183) in ChIP assay
Fri Dec 25 00:00:00 EST 2020
Transcriptomic and genetic approaches reveal an essential role of the NAC transcription factor SlNAP1 in the growth and defense response of tomato.
Horticulture research
Wang J,Zheng C,Shao X,Hu Z,Li J,Wang P,Wang A,Yu J,Shi K
Published figure using HA Tag monoclonal antibody (Product # 26183) in ChIP assay
Fri Dec 25 00:00:00 EST 2020
Pseudorabies Virus Infection of Epithelial Cells Leads to Persistent but Aberrant Activation of the NF-κB Pathway, Inhibiting Hallmark NF-κB-Induced Proinflammatory Gene Expression.
Journal of virology
Romero N,Van Waesberghe C,Favoreel HW
26183 was used in Flow cytometry/Cell sorting to report that infection of epithelial cells, including primary porcine respiratory epithelial cells, with the porcine alphaherpesvirus pseudorabies virus (PRV) results in the gradual and persistent activation of NF-κB, illustrated by proteasome-dependent degradation of the inhibitory NF-κB regulator IκB and nuclear translocation and phosphorylation of the NF-κB subunit p65.
Mon May 04 00:00:00 EDT 2020
Epigenetic activation of the small GTPase TCL contributes to colorectal cancer cell migration and invasion.
Oncogenesis
Chen B,Fan Z,Sun L,Chen J,Feng Y,Fan X,Xu Y
26183 was used in Western Blotting to identify a novel MRTF-A-hMOF-TCL axis that contributes to colorectal cancer metastasis.
Wed Sep 30 00:00:00 EDT 2020
Epigenetic activation of the small GTPase TCL contributes to colorectal cancer cell migration and invasion.
Oncogenesis
Chen B,Fan Z,Sun L,Chen J,Feng Y,Fan X,Xu Y
26183 was used in Western Blotting to identify a novel MRTF-A-hMOF-TCL axis that contributes to colorectal cancer metastasis.
Wed Sep 30 00:00:00 EDT 2020
Honokiol Inhibits Melanoma Growth by Targeting Keratin 18 in vitro and in vivo.
Frontiers in cell and developmental biology
Liu T,Liu H,Wang P,Hu Y,Yang R,Liu F,Kim HG,Dong Z,Liu K
26183 was used in Western Blot to show that honokiol inhibited the growth of melanoma cells in a dose and time-dependent manner.
Fri Dec 18 00:00:00 EST 2020
Honokiol Inhibits Melanoma Growth by Targeting Keratin 18 in vitro and in vivo.
Frontiers in cell and developmental biology
Liu T,Liu H,Wang P,Hu Y,Yang R,Liu F,Kim HG,Dong Z,Liu K
26183 was used in Western Blot to show that honokiol inhibited the growth of melanoma cells in a dose and time-dependent manner.
Fri Dec 18 00:00:00 EST 2020
Foot-and-Mouth Disease Virus 3B Protein Interacts with Pattern Recognition Receptor RIG-I to Block RIG-I-Mediated Immune Signaling and Inhibit Host Antiviral Response.
Journal of immunology (Baltimore, Md. : 1950)
Zhang X,Zhu Z,Wang C,Yang F,Cao W,Li P,Du X,Zhao F,Liu X,Zheng H
26183 was used in Western Blotting to demonstrate the significant role of 3B protein in suppression of type I IFN production and host antiviral response in both human embryonic kidney HEK293T cells and porcine kidney PK-15 cells.
Thu Oct 15 00:00:00 EDT 2020
IKIP Negatively Regulates NF-κB Activation and Inflammation through Inhibition of IKKα/β Phosphorylation.
Journal of immunology (Baltimore, Md. : 1950)
Wu H,Liu H,Zhao X,Zheng Y,Liu B,Zhang L,Gao C
26183 was used in Western Blotting to study the regulation of NF-kB signalling by IKK-interacting protein.
Wed Jan 15 00:00:00 EST 2020
Myocardin and myocardin-related transcription factor-A synergistically mediate actin cytoskeletal-dependent inhibition of liver fibrogenesis.
American journal of physiology. Gastrointestinal and liver physiology
Shi Z,Ren M,Rockey DC
26183 was used in Immunocytochemistry-immunoflourescence to show that dual expression of myocardin and MRTF-A in HSCs may represent novel therapeutic targets in liver fibrosis.
Sun Mar 01 00:00:00 EST 2020
Two interacting ATPases protect Mycobacterium tuberculosis from glycerol and nitric oxide toxicity.
Journal of bacteriology
Whitaker M,Ruecker N,Hartman T,Klevorn T,Andres J,Kim J,Rhee K,Ehrt S
26183 was used in Western Blotting to characterize two genes of unknown function, rv3679 and rv3680, for which inconsistent findings regarding their importance for virulence in mice have been reported.
Mon Jun 01 00:00:00 EDT 2020
Human apolipoprotein L1 interferes with mitochondrial function in Saccharomyces cerevisiae.
Molecular medicine reports
Chidiac M,Daher J,Boeckstaens M,Poelvoorde P,Badran B,Marini AM,Khalaf R,Vanhamme L
26183 was used in Western Blot, Immunocytochemistry to present evidence which suggests that APOL1 could be a physiological regulator of mitochondrial function.
Tue Sep 01 00:00:00 EDT 2020
Human apolipoprotein L1 interferes with mitochondrial function in Saccharomyces cerevisiae.
Molecular medicine reports
Chidiac M,Daher J,Boeckstaens M,Poelvoorde P,Badran B,Marini AM,Khalaf R,Vanhamme L
26183 was used in Western Blot, Immunocytochemistry to present evidence which suggests that APOL1 could be a physiological regulator of mitochondrial function.
Tue Sep 01 00:00:00 EDT 2020
Rac1 and EGFR cooperate to activate Pak in response to nutrient stress.
Biochemical and biophysical research communications
Lee SW,Commisso C
26183 was used in Western Blot to investigate how Pak activation in pancreatic ductal adenocarcinoma cells is influenced by glutamine-regulated signal transduction.
Thu Dec 10 00:00:00 EST 2020
A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1.
Journal of biochemistry
González de Cózar JM,Carretero-Junquera M,Ciesielski GL,Miettinen SM,Varjosalo M,Kaguni LS,Dufour E,Jacobs HT
26183 was used in Immunoprecipitation, Immunocytochemistry to show evidence that N-terminal hybrid-binding domain modulate the activity of Drosophila ribonuclease H1.
Sun Nov 01 00:00:00 EDT 2020
A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1.
Journal of biochemistry
González de Cózar JM,Carretero-Junquera M,Ciesielski GL,Miettinen SM,Varjosalo M,Kaguni LS,Dufour E,Jacobs HT
26183 was used in Immunoprecipitation, Immunocytochemistry to show evidence that N-terminal hybrid-binding domain modulate the activity of Drosophila ribonuclease H1.
Sun Nov 01 00:00:00 EDT 2020
Structure and Multitasking of the c-di-GMP-Sensing Cellulose Secretion Regulator BcsE.
mBio
Zouhir S,Abidi W,Caleechurn M,Krasteva PV
26183 was used in Western Blotting to suggest that BcsE acts on multiple levels to fine-tune bacterial cellulose secretion, from the early stages of secretion system assembly to the maintenance of a membrane-proximal pool of dimeric c-di-GMP for processive synthase activation.
Tue Aug 11 00:00:00 EDT 2020
Structure and Multitasking of the c-di-GMP-Sensing Cellulose Secretion Regulator BcsE.
mBio
Zouhir S,Abidi W,Caleechurn M,Krasteva PV
26183 was used in Western Blotting to suggest that BcsE acts on multiple levels to fine-tune bacterial cellulose secretion, from the early stages of secretion system assembly to the maintenance of a membrane-proximal pool of dimeric c-di-GMP for processive synthase activation.
Tue Aug 11 00:00:00 EDT 2020
Protocol for In Vivo Evaluation and Use of Destabilizing Domains in the Eye, Liver, and Beyond.
STAR protocols
Ramadurgum P,Daniel S,Hulleman JD
26183 was used in Immunoprecipitation to implement and evaluate a DD-POI in mouse ocular and hepatic tissue.
Fri Sep 18 00:00:00 EDT 2020
Protocol for In Vivo Evaluation and Use of Destabilizing Domains in the Eye, Liver, and Beyond.
STAR protocols
Ramadurgum P,Daniel S,Hulleman JD
26183 was used in Immunoprecipitation to implement and evaluate a DD-POI in mouse ocular and hepatic tissue.
Fri Sep 18 00:00:00 EDT 2020
UBB pseudogene 4 encodes functional ubiquitin variants.
Nature communications
Dubois ML,Meller A,Samandi S,Brunelle M,Frion J,Brunet MA,Toupin A,Beaudoin MC,Jacques JF,Lévesque D,Scott MS,Lavigne P,Roucou X,Boisvert FM
26183 was used in Western Blot to suggest that a subset of proteins reported as ubiquitin targets may instead be modified by ubiquitin variants that are the products of wrongly annotated pseudogenes and induce different functional effects.
Wed Mar 11 00:00:00 EDT 2020
UBB pseudogene 4 encodes functional ubiquitin variants.
Nature communications
Dubois ML,Meller A,Samandi S,Brunelle M,Frion J,Brunet MA,Toupin A,Beaudoin MC,Jacques JF,Lévesque D,Scott MS,Lavigne P,Roucou X,Boisvert FM
26183 was used in Western Blot to suggest that a subset of proteins reported as ubiquitin targets may instead be modified by ubiquitin variants that are the products of wrongly annotated pseudogenes and induce different functional effects.
Wed Mar 11 00:00:00 EDT 2020
SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability.
International journal of molecular sciences
Yu M,Shi X,Ren M,Liu L,Qi H,Zhang C,Zou J,Qiu X,Zhu WG,Zhang YE,Wang W,Luo J
26183 was used in Immunoprecipitation to demonstrate that STRAP acetylation plays an important role in p53-mediated cell cycle arrest and apoptosis.
Tue Jun 09 00:00:00 EDT 2020
SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability.
International journal of molecular sciences
Yu M,Shi X,Ren M,Liu L,Qi H,Zhang C,Zou J,Qiu X,Zhu WG,Zhang YE,Wang W,Luo J
26183 was used in Immunoprecipitation to demonstrate that STRAP acetylation plays an important role in p53-mediated cell cycle arrest and apoptosis.
Tue Jun 09 00:00:00 EDT 2020
Environmental stress perception activates structural remodeling of extant Streptococcus mutans biofilms.
NPJ biofilms and microbiomes
Marx P,Sang Y,Qin H,Wang Q,Guo R,Pfeifer C,Kreth J,Merritt J
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Fri Mar 27 00:00:00 EDT 2020
Function of P2X4 Receptors Is Directly Modulated by a 1:1 Stoichiometric Interaction With 5-HT3A Receptors.
Frontiers in cellular neuroscience
Soto P,Gaete PS,Fuentes C,Lozano B,Naulin PA,Figueroa XF,Barrera NP
26183 was used in Immunocytochemistry-immunoflourescence to study binding stoichiometry and the role of P2X4 receptor activation by ATP.
Mon Sep 28 00:00:00 EDT 2020
Function of P2X4 Receptors Is Directly Modulated by a 1:1 Stoichiometric Interaction With 5-HT3A Receptors.
Frontiers in cellular neuroscience
Soto P,Gaete PS,Fuentes C,Lozano B,Naulin PA,Figueroa XF,Barrera NP
26183 was used in Immunocytochemistry-immunoflourescence to study binding stoichiometry and the role of P2X4 receptor activation by ATP.
Mon Sep 28 00:00:00 EDT 2020
Function of P2X4 Receptors Is Directly Modulated by a 1:1 Stoichiometric Interaction With 5-HT3A Receptors.
Frontiers in cellular neuroscience
Soto P,Gaete PS,Fuentes C,Lozano B,Naulin PA,Figueroa XF,Barrera NP
26183 was used in Immunocytochemistry-immunoflourescence to study binding stoichiometry and the role of P2X4 receptor activation by ATP.
Mon Sep 28 00:00:00 EDT 2020
CaaX-Like Protease of Cyanobacterial Origin Is Required for Complex Plastid Biogenesis in Malaria Parasites.
mBio
Meister TR,Tang Y,Pulkoski-Gross MJ,Yeh E
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Tue Oct 06 00:00:00 EDT 2020
CaaX-Like Protease of Cyanobacterial Origin Is Required for Complex Plastid Biogenesis in Malaria Parasites.
mBio
Meister TR,Tang Y,Pulkoski-Gross MJ,Yeh E
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Tue Oct 06 00:00:00 EDT 2020
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1.
Nature communications
Du Y,Hultquist JF,Zhou Q,Olson A,Tseng Y,Zhang TH,Hong M,Tang K,Chen L,Meng X,McGregor MJ,Dai L,Gong D,Martin-Sancho L,Chanda S,Li X,Bensenger S,Krogan NJ,Sun R
26183 was used in Western Blotting to identify a mutant of NS1, D92Y, results in a loss of interaction with CPSF1.
Fri May 15 00:00:00 EDT 2020
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1.
Nature communications
Du Y,Hultquist JF,Zhou Q,Olson A,Tseng Y,Zhang TH,Hong M,Tang K,Chen L,Meng X,McGregor MJ,Dai L,Gong D,Martin-Sancho L,Chanda S,Li X,Bensenger S,Krogan NJ,Sun R
26183 was used in Western Blotting to identify a mutant of NS1, D92Y, results in a loss of interaction with CPSF1.
Fri May 15 00:00:00 EDT 2020
Molecular Basis of Zinc-Dependent Endocytosis of Human ZIP4 Transceptor.
Cell reports
Zhang C,Sui D,Zhang T,Hu J
26183 was used in Western Blot, In vitro Assay to provide a paradigm on post-translational regulation of nutrient transporters.
Tue Apr 28 00:00:00 EDT 2020
Molecular Basis of Zinc-Dependent Endocytosis of Human ZIP4 Transceptor.
Cell reports
Zhang C,Sui D,Zhang T,Hu J
26183 was used in Western Blot, In vitro Assay to provide a paradigm on post-translational regulation of nutrient transporters.
Tue Apr 28 00:00:00 EDT 2020
Molecular Basis of Zinc-Dependent Endocytosis of Human ZIP4 Transceptor.
Cell reports
Zhang C,Sui D,Zhang T,Hu J
26183 was used in Western Blot, In vitro Assay to provide a paradigm on post-translational regulation of nutrient transporters.
Tue Apr 28 00:00:00 EDT 2020
Protocol for Designing Small-Molecule-Regulated Destabilizing Domains for In Vitro Use.
STAR protocols
Ramadurgum P,Hulleman JD
26183 was used in Western Blotting to describe a platform for achieving identification of novel (and potentially synergistic) small-molecule stabilizers.
Fri Sep 18 00:00:00 EDT 2020
Protocol for Designing Small-Molecule-Regulated Destabilizing Domains for In Vitro Use.
STAR protocols
Ramadurgum P,Hulleman JD
26183 was used in Western Blotting to describe a platform for achieving identification of novel (and potentially synergistic) small-molecule stabilizers.
Fri Sep 18 00:00:00 EDT 2020
Regulation of the thrombin/protease-activated receptor 1 axis by chemokine (CXC motif) receptor 4.
The Journal of biological chemistry
Gao X,Cheng YH,Enten GA,DeSantis AJ,Gaponenko V,Majetschak M
26183 was used in Proximity Ligation Assay (PLA) to suggest that CXCR4:PAR1 heteromerization enhances thrombin-induced G protein signaling of PAR1 and PAR1-mediated endothelial barrier disruption.
Fri Oct 30 00:00:00 EDT 2020
A MAGEL2-deubiquitinase complex modulates the ubiquitination of circadian rhythm protein CRY1.
PloS one
Carias KV,Zoeteman M,Seewald A,Sanderson MR,Bischof JM,Wevrick R
26183 was used in Western Blotting to demonstrate that MAGEL2 modulates the ubiquitination of CRY1.
Mon Jul 06 00:00:00 EDT 2020
Simultaneous Control of Endogenous and User-Defined Genetic Pathways Using Unique ecDHFR Pharmacological Chaperones.
Cell chemical biology
Ramadurgum P,Woodard DR,Daniel S,Peng H,Mallipeddi PL,Niederstrasser H,Mihelakis M,Chau VQ,Douglas PM,Posner BA,Hulleman JD
26183 was used in Western Blot to identify potential ecDHFR DD stabilizing compounds in an unbiased fashion.
Thu May 21 00:00:00 EDT 2020
An RNA Repair Operon Regulated by Damaged tRNAs.
Cell reports
Hughes KJ,Chen X,Burroughs AM,Aravind L,Wolin SL
26183 was used in Western Blotting to reveal a signaling pathway involving broken tRNAs and implicate the operon in tRNA repair.
Tue Dec 22 00:00:00 EST 2020
A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development.
Developmental cell
Kong JH,Young CB,Pusapati GV,Patel CB,Ho S,Krishnan A,Lin JI,Devine W,Moreau de Bellaing A,Athni TS,Aravind L,Gunn TM,Lo CW,Rohatgi R
26183 was used in Western Blotting to conclude that genetic interactions can arise from biochemical mechanisms that calibrate morphogen signaling strength.
Mon Nov 23 00:00:00 EST 2020
The HY5 and MYB15 transcription factors positively regulate cold tolerance in tomato via the CBF pathway.
Plant, cell & environment
Zhang L,Jiang X,Liu Q,Ahammed GJ,Lin R,Wang L,Shao S,Yu J,Zhou Y
26183 was used in Western Blotting to investigate the role of CBFs in plant cold response and survival.
Sun Nov 01 00:00:00 EDT 2020
Elucidation of proteostasis defects caused by osteogenesis imperfecta mutations in the collagen-α2(I) C-propeptide domain.
The Journal of biological chemistry
Doan ND,Hosseini AS,Bikovtseva AA,Huang MS,DiChiara AS,Papa LJ,Koller A,Shoulders MD
26183 was used in Western Blotting to integrate biochemical and cellular approaches to illuminate the proteostasis defects associated with osteogenesis imperfecta-causing mutations within the collagen-α2(I) C-Pro domain.
Fri Jul 17 00:00:00 EDT 2020
Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling.
The Journal of biological chemistry
Cope NJ,Novak B,Liu Z,Cavallo M,Gunderwala AY,Connolly M,Wang Z
26183 was used in Western Blot to investigate if the variant BRAFD594G, a kinase-dead representative of class 3 mutation-derived BRAF variants, has a higher dimerization potential as compared with WT BRAF.
Fri Feb 21 00:00:00 EST 2020
Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses.
Cell death & disease
Liu L,Chen S,Yu M,Ge C,Ren M,Liu B,Yang X,Christian TW,Hou YM,Zou J,Zhu WG,Luo J
26183 was used in Western Blotting to demonstrate that acetylation is an important regulation mechanism for HSD17B10 and may provide insight into interrupting the development of AD.
Thu Jul 23 00:00:00 EDT 2020
The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I.
Science advances
Zhou C,Miao Y,Cui Z,ShiYang X,Zhang Y,Xiong B
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Wed Apr 01 00:00:00 EDT 2020
The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I.
Science advances
Zhou C,Miao Y,Cui Z,ShiYang X,Zhang Y,Xiong B
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Wed Apr 01 00:00:00 EDT 2020
Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation.
The Journal of biological chemistry
Nagareddy B,Khan A,Kim H
26183 was used in Western Blot to present evidence that FAAP20 is acetylated by the acetyltransferase p300/CBP on lysine 152.
Fri Oct 02 00:00:00 EDT 2020
A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites.
PLoS biology
Tang Y,Meister TR,Walczak M,Pulkoski-Gross MJ,Hari SB,Sauer RT,Amberg-Johnson K,Yeh E
26183 was used in Western Blotting to perform a mutagenesis screen for essential genes required for apicoplast biogenesis in Plasmodium falciparum.
Fri Feb 01 00:00:00 EST 2019
HDA9-PWR-HOS15 Is a Core Histone Deacetylase Complex Regulating Transcription and Development.
Plant physiology
Mayer KS,Chen X,Sanders D,Chen J,Jiang J,Nguyen P,Scalf M,Smith LM,Zhong X
26183 was used in Chromatin immunoprecipitation to determine how deacetylases perform specialised molecular and biological functions in plants.
Wed May 01 00:00:00 EDT 2019
HDA9-PWR-HOS15 Is a Core Histone Deacetylase Complex Regulating Transcription and Development.
Plant physiology
Mayer KS,Chen X,Sanders D,Chen J,Jiang J,Nguyen P,Scalf M,Smith LM,Zhong X
26183 was used in Chromatin immunoprecipitation to determine how deacetylases perform specialised molecular and biological functions in plants.
Wed May 01 00:00:00 EDT 2019
The ESCRT-0 Protein HRS Interacts with the Human T Cell Leukemia Virus Type 2 Antisense Protein APH-2 and Suppresses Viral Replication.
Journal of virology
Martini F,Arone C,Hasset A,Hall WW,Sheehy N
26183 was used in Western Blotting to characterize the interaction between HRS and APH-2 and to investigate the impact of HRS on the life cycle of HTLV-2.
Thu Dec 12 00:00:00 EST 2019
SIRT4 regulates PTEN stability through IDE in response to cellular stresses.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liu M,Wang Z,Ren M,Yang X,Liu B,Qi H,Yu M,Song S,Chen S,Liu L,Zhang Y,Zou J,Zhu WG,Yin Y,Luo J
26183 was used in Western Blotting to demonstrate that Sirtuin 4 interacts with PTEN and regulates its stability.
Mon Apr 01 00:00:00 EDT 2019
In vitro affinity maturation of antibody against membrane-bound GPCR molecules.
Applied microbiology and biotechnology
Wang J,An L,Zhao Y,Zhang C,Li S,Ye C,Jing S,Hang H
26183 was used in Flow cytometry/Cell sorting to describe a method that will not only be used for the affinity maturation of antibodies against GPCRs but will also be used to mature antibodies for other types of proteins where the conformation/activity of which depends on the proper membrane environment.
Sun Sep 01 00:00:00 EDT 2019
A novel human Cdh1 mutation impairs anaphase promoting complex/cyclosome activity resulting in microcephaly, psychomotor retardation, and epilepsy.
Journal of neurochemistry
Rodríguez C,Sánchez-Morán I,Álvarez S,Tirado P,Fernández-Mayoralas DM,Calleja-Pérez B,Almeida Á,Fernández-Jaén A
26183 was used in Western Blotting to indicate that the loss of function of APC/C-Cdh1 caused by Cdh1 Asp187Gly mutation is a new cause of prenatal microcephaly, psychomotor retardation, and severe epilepsy.
Tue Oct 01 00:00:00 EDT 2019
Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors.
Gene therapy
Bai RY,Esposito D,Tam AJ,McCormick F,Riggins GJ,Wade Clapp D,Staedtke V
26183 was used in Western Blotting to explore the feasibility of restoring Ras GTPase via exogenous expression of various GTPase-activating protein-related domain constructs, via gene delivery using a panel of adeno-associated virus vectors in malignant peripheral nerve sheath tumors and human Schwann cells.
Sat Jun 01 00:00:00 EDT 2019
TRESK (K2P18.1) Background Potassium Channel Is Activated by Novel-Type Protein Kinase C via Dephosphorylation.
Molecular pharmacology
Pergel E,Lengyel M,Enyedi P,Czirják G
26183 was used in Western Blotting to investigate the mechanism of protein kinase C-dependent TRESK regulation.
Sat Jun 01 00:00:00 EDT 2019
LncRNA LINC00460 promotes EMT in head and neck squamous cell carcinoma by facilitating peroxiredoxin-1 into the nucleus.
Journal of experimental & clinical cancer research : CR
Jiang Y,Cao W,Wu K,Qin X,Wang X,Li Y,Yu B,Zhang Z,Wang X,Yan M,Xu Q,Zhang J,Chen W
26183 was used in Western Blotting to determine the potential clinical applications of LINC00460 and elucidate the mechanisms by which LINC00460 affects the development and progression of head and neck squamous cell carcinoma (HNSCC).
Tue Aug 20 00:00:00 EDT 2019
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
Molecular cell
Wang Z,Yang X,Liu C,Li X,Zhang B,Wang B,Zhang Y,Song C,Zhang T,Liu M,Liu B,Ren M,Jiang H,Zou J,Liu X,Zhang H,Zhu WG,Yin Y,Zhang Z,Gu W,Luo J
26183 was used in Immunocytochemistry-immunofluorescence to uncover mechanisms of an anti-stress pathway through which acetylation on PHF5A promotes the cancer cells' capacity for stress resistance and consequently contributes to colon carcinogenesis.
Thu Jun 20 00:00:00 EDT 2019
GTPase-activating protein Rasal1 associates with ZAP-70 of the TCR and negatively regulates T-cell tumor immunity.
Nature communications
Thaker YR,Raab M,Strebhardt K,Rudd CE
26183 was used in Western Blotting to identify the role of Rasal1 in the regulation of T-cell activation and tumour immunity.
Tue Oct 22 00:00:00 EDT 2019
In Vitro Screening Platforms for Identifying Autophagy Modulators in Mammalian Cells.
Methods in molecular biology (Clifton, N.J.)
Seranova E,Ward C,Chipara M,Rosenstock TR,Sarkar S
26183 was used in Western Blotting to present stringent secondary autophagy assays to characterize the autophagy modulators arising from primary screening of mammalian cells.
Thu Jun 06 00:00:00 EDT 2019
Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae.
BMC biology
Kulkarni SD,Zhou F,Sen ND,Zhang H,Hinnebusch AG,Lorsch JR
26183 was used in Western Blotting to show that alterations in the translation of specific upstream open reading frames by temperature can regulate gene expression in S. cerevisiae.
Fri Dec 06 00:00:00 EST 2019
Gigaxonin E3 ligase governs ATG16L1 turnover to control autophagosome production.
Nature communications
Scrivo A,Codogno P,Bomont P
26183 was used in Proximity Ligation Assay to unveil the fundamental mechanisms of the control of autophagosome formation, and provide a molecular switch to fine-tune the activation of autophagy.
Fri Feb 15 00:00:00 EST 2019
HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression.
iScience
Patel N,Wang J,Shiozawa K,Jones KB,Zhang Y,Prokop JW,Davenport GG,Nihira NT,Hao Z,Wong D,Brandsmeier L,Meadows SK,Sampaio AV,Werff RV,Endo M,Capecchi MR,McNagny KM,Mak TW,Nielsen TO,Underhill TM,Myers RM,Kondo T,Su L
26183 was used in Western Blotting to uncover a new HDAC2-dependent pathway that integrates reversible acetylation signaling to the anticancer ubiquitin response.
Fri Mar 29 00:00:00 EDT 2019
The Heat Shock Response in Yeast Maintains Protein Homeostasis by Chaperoning and Replenishing Proteins.
Cell reports
Mühlhofer M,Berchtold E,Stratil CG,Csaba G,Kunold E,Bach NC,Sieber SA,Haslbeck M,Zimmer R,Buchner J
26183 was used in Western Blot to support the concept that the HSR is modular with distinct programs dependent on the severity of the stress.
Tue Dec 24 00:00:00 EST 2019
Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration.
The Journal of clinical investigation
Xie L,Yin A,Nichenko AS,Beedle AM,Call JA,Yin H
26183 was used in Western Blotting to demonstrate that satellite cells are in an intrinsic hypoxic state in vivo and express hypoxia-inducible factor 2A.
Fri Jun 01 00:00:00 EDT 2018
The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations.
Molecular cell
Chen L,Chen JY,Huang YJ,Gu Y,Qiu J,Qian H,Shao C,Zhang X,Hu J,Li H,He S,Zhou Y,Abdel-Wahab O,Zhang DE,Fu XD
26183 was used in Western Blotting to study the importance of the augmented R-loop as a unifying mechanism for myelodysplastic syndromes induced by high-risk splicing factor mutations.
Thu Feb 01 00:00:00 EST 2018
Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins.
Nature protocols
Elegheert J,Behiels E,Bishop B,Scott S,Woolley RE,Griffiths SC,Byrne EFX,Chang VT,Stuart DI,Jones EY,Siebold C,Aricescu AR
26183 was used in Western Blotting to describe the design and step-by-step application of a lentiviral plasmid suite, termed pHR-CMV-TetO2, for the constitutive or inducible large-scale production of soluble and membrane proteins in HEK293 cell lines.
Sat Dec 01 00:00:00 EST 2018
SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.
Cancer research
Yang X,Wang Z,Li X,Liu B,Liu M,Liu L,Chen S,Ren M,Wang Y,Yu M,Wang B,Zou J,Zhu WG,Yin Y,Gu W,Luo J
26183 was used in Western Blotting to examine the mechanisms by which the driving of cancer cell proliferation by mitochondrial serine hydroxymethyltransferase is regulated.
Mon Jan 15 00:00:00 EST 2018
Light Signaling-Dependent Regulation of Photoinhibition and Photoprotection in Tomato.
Plant physiology
Wang F,Wu N,Zhang L,Ahammed GJ,Chen X,Xiang X,Zhou J,Xia X,Shi K,Yu J,Foyer CH,Zhou Y
26183 was used in Chromatin immunoprecipitation to show that low-red/far-red ratio light conditions significantly alleviate PSII and PSI photoinhibition in the shade leaves of tomato (Solanum lycopersicum) plants.
Thu Feb 01 00:00:00 EST 2018
Oncoprotein AEG-1 is an endoplasmic reticulum RNA-binding protein whose interactome is enriched in organelle resident protein-encoding mRNAs.
RNA (New York, N.Y.)
Hsu JC,Reid DW,Hoffman AM,Sarkar D,Nicchitta CV
26183 was used in Immunoprecipitation to report that AEG-1 is an endoplasmic reticulum resident integral membrane RNA-binding protein.
Tue May 01 00:00:00 EDT 2018
A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye - Implications for Ocular Gene Therapy.
Investigative ophthalmology & visual science
Datta S,Renwick M,Chau VQ,Zhang F,Nettesheim ER,Lipinski DM,Hulleman JD
26183 was used in Western Blotting to study the effect of a destabilising dihydrofolate reductase domain on protein expression in the retina.
Mon Oct 01 00:00:00 EDT 2018
Cyclin E2-CDK2 mediates SAMHD1 phosphorylation to abrogate its restriction of HBV replication in hepatoma cells.
FEBS letters
Hu J,Qiao M,Chen Y,Tang H,Zhang W,Tang D,Pi S,Dai J,Tang N,Huang A,Hu Y
26183 was used in Immunoprecipitation to provide evidence that CDK2 has a greater role in regulating SAMHD1 phosphorylation and HBV replication than CDK1 or CDK6.
Fri Jun 01 00:00:00 EDT 2018
Cyclin E2-CDK2 mediates SAMHD1 phosphorylation to abrogate its restriction of HBV replication in hepatoma cells.
FEBS letters
Hu J,Qiao M,Chen Y,Tang H,Zhang W,Tang D,Pi S,Dai J,Tang N,Huang A,Hu Y
26183 was used in Immunoprecipitation to provide evidence that CDK2 has a greater role in regulating SAMHD1 phosphorylation and HBV replication than CDK1 or CDK6.
Fri Jun 01 00:00:00 EDT 2018
Cytosolic Delivery of Multidomain Cargos by the N Terminus of Pasteurella multocida Toxin.
Infection and immunity
Clemons NC,Bannai Y,Haywood EE,Xu Y,Buschbach JD,Ho M,Wilson BA
26183 was used in Western Blotting to study the cytosolic delivery of multi-domain cargos by Pasteurella multocida toxin.
Wed Aug 01 00:00:00 EDT 2018
Switchable genome editing via genetic code expansion.
Scientific reports
Suzuki T,Asami M,Patel SG,Luk LYP,Tsai YH,Perry ACF
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Tue Jul 03 00:00:00 EDT 2018
Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR.
Nature communications
Dai Y,Zhang A,Shan S,Gong Z,Zhou Z
26183 was used in Western Blotting to characterise the 1.76-A crystal structure of Tudor-interacting repair regulator in complex with P53-binding protein 1 tandem Tudor domain.
Tue May 29 00:00:00 EDT 2018
Newcastle Disease Virus V Protein Inhibits Cell Apoptosis and Promotes Viral Replication by Targeting CacyBP/SIP.
Frontiers in cellular and infection microbiology
Chu Z,Wang C,Tang Q,Shi X,Gao X,Ma J,Lu K,Han Q,Jia Y,Wang X,Adam FEA,Liu H,Xiao S,Wang X,Yang Z
26183 was used in Western blotting following immunoprecipitation to study the interaction between Newcastle disease virus V protein with CacyBP/SIP protein in the regulation of cell apoptosis and viral replication.
Thu Aug 29 00:00:00 EDT 2019
Cox15 interacts with the cytochrome bc1 dimer within respiratory supercomplexes as well as in the absence of cytochrome c oxidase.
The Journal of biological chemistry
Herwaldt EJ,Rivett ED,White AJ,Hegg EL
26183 was used in Western Blotting to investigate the protein-protein interactions that involve Cox15 in S. cerevisiae.
Fri Oct 19 00:00:00 EDT 2018
A compartmentalized signaling network mediates crossover control in meiosis.
eLife
Zhang L,Köhler S,Rillo-Bohn R,Dernburg AF
26183 was used in Western Blotting to investigate the functions of the proteins ZHP-1, ZHP-2, and ZHP-4.
Fri Mar 09 00:00:00 EST 2018
A compartmentalized signaling network mediates crossover control in meiosis.
eLife
Zhang L,Köhler S,Rillo-Bohn R,Dernburg AF
26183 was used in Western Blotting to investigate the functions of the proteins ZHP-1, ZHP-2, and ZHP-4.
Fri Mar 09 00:00:00 EST 2018
The Na+ -coupled glucose transporter SGLT2 interacts with its accessory unit MAP17 in vitro and their expressions overlap in the renal proximal tubule.
FEBS letters
Calado J,Santos AR,Aires I,Lebre F,Nolasco F,Rueff J,Ramalho J
26183 was used in Western Blotting to provide the rationale behind SGLT2 activation by MAP17 as well the similarity of the SLC5A2 and PDZK1IP1 glucosuric phenotypes.
Mon Oct 01 00:00:00 EDT 2018
Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.
Nature communications
He K,Ma X,Xu T,Li Y,Hodge A,Zhang Q,Torline J,Huang Y,Zhao J,Ling K,Hu J
26183 was used in Immunocytochemistry-immunoflourescence to reveal that tubulin polyglutamylation is a major contributor for cilia signalling and suggest a potential therapeutic strategy to correct signalling defects in ciliopathies.
Fri Aug 17 00:00:00 EDT 2018
RIP2 filament formation is required for NOD2 dependent NF-κB signalling.
Nature communications
Pellegrini E,Desfosses A,Wallmann A,Schulze WM,Rehbein K,Mas P,Signor L,Gaudon S,Zenkeviciute G,Hons M,Malet H,Gutsche I,Sachse C,Schoehn G,Oschkinat H,Cusack S
26183 was used in Western Blotting to demonstrate that full-length RIP2 can form long filaments mediated by its caspase recruitment domain, in common with other innate immune adaptor proteins.
Tue Oct 02 00:00:00 EDT 2018
The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.
PloS one
Friesen WJ,Johnson B,Sierra J,Zhuo J,Vazirani P,Xue X,Tomizawa Y,Baiazitov R,Morrill C,Ren H,Babu S,Moon YC,Branstrom A,Mollin A,Hedrick J,Sheedy J,Elfring G,Weetall M,Colacino JM,Welch EM,Peltz SW
26183 was used in Western Blotting to investigate the readthrough activities of the four major gentamicin complex components.
Tue Apr 09 00:00:00 EDT 2019
RNA targeting with CRISPR-Cas13.
Nature
Abudayyeh OO,Gootenberg JS,Essletzbichler P,Han S,Joung J,Belanto JJ,Verdine V,Cox DBT,Kellner MJ,Regev A,Lander ES,Voytas DF,Ting AY,Zhang F
26183 was used in Immunoprecipitation to establish CRISPR-Cas13a as a flexible platform for studying RNA in mammalian cells and therapeutic development.
Thu Oct 12 00:00:00 EDT 2017
A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Cancer cell
Mello SS,Valente LJ,Raj N,Seoane JA,Flowers BM,McClendon J,Bieging-Rolett KT,Lee J,Ivanochko D,Kozak MM,Chang DT,Longacre TA,Koong AC,Arrowsmith CH,Kim SK,Vogel H,Wood LD,Hruban RH,Curtis C,Attardi LD
26183 was used in Western Blotting to analyse pancreatic cancer development in mice expressing p53 transcriptional activation domain mutants.
Mon Oct 09 00:00:00 EDT 2017
Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells.
The Journal of clinical investigation
Wasserman GA,Szymaniak AD,Hinds AC,Yamamoto K,Kamata H,Smith NM,Hilliard KL,Carrieri C,Labadorf AT,Quinton LJ,Ai X,Varelas X,Chen F,Mizgerd JP,Fine A,O'Carroll D,Jones MR
26183 was used in Immunoprecipitation to observe that Piwi-like Miwi2 mRNA is expressed in murine lung epithelial cells, and is induced during pneumonia.
Mon Oct 02 00:00:00 EDT 2017
The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity.
Molecular cell
Feng Q,Jagannathan S,Bradley RK
26183 was used in Western Blotting to study the role of UPF1 in regulated protein decay.
Thu Jul 20 00:00:00 EDT 2017
ZRF1 is a novel S6 kinase substrate that drives the senescence programme.
The EMBO journal
Barilari M,Bonfils G,Treins C,Koka V,De Villeneuve D,Fabrega S,Pende M
26183 was used in immunoprecipitation to determine the effect of constitutive activation of mammalian target of rapamycin complex 1 on premature senescence activation in fibroblasts
Wed Mar 15 00:00:00 EDT 2017
STK33 Promotes Growth and Progression of Pancreatic Cancer as a Critical Downstream Mediator of HIF1α.
Cancer research
Kong F,Kong X,Du Y,Chen Y,Deng X,Zhu J,Du J,Li L,Jia Z,Xie D,Li Z,Xie K
Fri Dec 15 00:00:00 EST 2017
APC/CCdh1-Rock2 pathway controls dendritic integrity and memory.
Proceedings of the National Academy of Sciences of the United States of America
Bobo-Jiménez V,Delgado-Esteban M,Angibaud J,Sánchez-Morán I,de la Fuente A,Yajeya J,Nägerl UV,Castillo J,Bolaños JP,Almeida A
26183 was used in immunoprecipitation and western blot to report that the anaphase-promoting complex/cyclosome-mediated degradation of Rock2 maintains the dendritic network, memory formation, and neuronal survival
Tue Apr 25 00:00:00 EDT 2017
Reconstitution of Torso signaling in cultured cells suggests a role for both Trunk and Torso-like in receptor activation.
Development (Cambridge, England)
Amarnath S,Stevens LM,Stein DS
26183 was used in immunocytochemistry to study Torso, Trunk, and Torsolike in Drosophilia
Wed Feb 15 00:00:00 EST 2017
Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma.
Molecular cancer research : MCR
Zhu F,Hwang B,Miyamoto S,Rui L
26183 was used in Western Blotting to demonstrate that the nuclear import of JAK1 is essential for the optimal fitness of activated B-cell-like diffuse large B-cell lymphoma cells.
Wed Mar 01 00:00:00 EST 2017
Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse.
Transgenic research
Kriz V,Krausova M,Buresova P,Dobes J,Hrckulak D,Babosova O,Svec J,Korinek V
26183 was used in Western Blotting to suggest the HA tag-specific antibody can be employed to characterize the biochemical features of Lgr4 and to identify possible biding partners of the protein in cells derived from various mouse tissues.
Sun Oct 01 00:00:00 EDT 2017
Real-time genomic profiling of histiocytoses identifies early-kinase domain BRAF alterations while improving treatment outcomes.
JCI insight
Lee LH,Gasilina A,Roychoudhury J,Clark J,McCormack FX,Pressey J,Grimley MS,Lorsbach R,Ali S,Bailey M,Stephens P,Ross JS,Miller VA,Nassar NN,Kumar AR
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Thu Feb 09 00:00:00 EST 2017
The Malaria Parasite Cyclin H Homolog PfCyc1 Is Required for Efficient Cytokinesis in Blood-Stage Plasmodium falciparum.
mBio
Robbins JA,Absalon S,Streva VA,Dvorin JD
Published figure using HA Tag monoclonal antibody (Product # 26183) in Western Blot
Tue Jun 13 00:00:00 EDT 2017
Endogenous C-terminal Tagging by CRISPR/Cas9 in Trypanosoma cruzi.
Bio-protocol
Lander N,Chiurillo MA,Vercesi AE,Docampo R
26183 was used in Western Blotting to achieve the C-terminal tagging of endogenous proteins in Trypanosoma cruzi using CRISPR/Cas-9.
Sat May 20 00:00:00 EDT 2017
Mitochondrial Ferredoxin Determines Vulnerability of Cells to Copper Excess.
Cell chemical biology
Vallières C,Holland SL,Avery SV
26183 was used in Western Blotting to study the role of mitochondrial ferredoxin as an important target in determining vulnerability to copper excess.
Thu Oct 19 00:00:00 EDT 2017
Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH).
PLoS genetics
Yang J,Kim MJ,Yoon W,Kim EY,Kim H,Lee Y,Min B,Kang KS,Son JH,Park HT,Chung J,Koh H
26183 was used in Western Blotting to investigate the potential of isocitrate and its derivatives as novel treatments for Parkinson's disease associated with DJ-1 dysfunction.
Tue Aug 01 00:00:00 EDT 2017
Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1.
PloS one
Walsh NM,Wuthrich M,Wang H,Klein B,Hull CM
26183 was used in immunocytochemistry to assess the role of Dectin-1 and other C-type lectins in interactions with C. neoformans spores
Thu Aug 17 00:00:00 EDT 2017
Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway.
Science advances
Zhang T,Liu J,Fellner M,Zhang C,Sui D,Hu J
26183 was used in Western Blotting to elucidate the crystal structures of Zrt/lrt-like proteins, and how this relates to their role in metal transport.
Tue Aug 01 00:00:00 EDT 2017
The 9aaTAD Is Exclusive Activation Domain in Gal4.
PloS one
Piskacek M,Havelka M,Rezacova M,Knight A
26183 was used in western blot to investigate the functions of all Gal4 activation domains
Mon Aug 28 00:00:00 EDT 2017
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature
Lee AS,Kranzusch PJ,Doudna JA,Cate JH
26183 was used in western blot to identify a cap-dependent translation mechanism that is independent of eIF4E
Thu Aug 04 00:00:00 EDT 2016
Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells.
Nucleic acids research
Renaud E,Barascu A,Rosselli F
26183 was used in western blot to study how the Fanconi anemia pathway promotes homologous recombination at stalled replication forks
Fri Jan 29 00:00:00 EST 2016
Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
The EMBO journal
Sellier C,Campanari ML,Julie Corbier C,Gaucherot A,Kolb-Cheynel I,Oulad-Abdelghani M,Ruffenach F,Page A,Ciura S,Kabashi E,Charlet-Berguerand N
26183 was used in Western Blotting to indicate that partial loss of function of C9ORF72 synergizes with Ataxin-2 toxicity, suggesting a double-hit pathological mechanism in ALS-FTD.
Wed Jun 15 00:00:00 EDT 2016
Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
The EMBO journal
Sellier C,Campanari ML,Julie Corbier C,Gaucherot A,Kolb-Cheynel I,Oulad-Abdelghani M,Ruffenach F,Page A,Ciura S,Kabashi E,Charlet-Berguerand N
26183 was used in Western Blotting to indicate that partial loss of function of C9ORF72 synergizes with Ataxin-2 toxicity, suggesting a double-hit pathological mechanism in ALS-FTD.
Wed Jun 15 00:00:00 EDT 2016
Detection of Antibodies in Blood Plasma Using Bioluminescent Sensor Proteins and a Smartphone.
Analytical chemistry
Arts R,den Hartog I,Zijlema SE,Thijssen V,van der Beelen SH,Merkx M
26183 was used to describe a new sensor platform (LUMABS) that allows detection of antibodies directly in solution using a smartphone
Tue Apr 19 00:00:00 EDT 2016
RalF-Mediated Activation of Arf6 Controls Rickettsia typhi Invasion by Co-Opting Phosphoinositol Metabolism.
Infection and immunity
Rennoll-Bankert KE,Rahman MS,Guillotte ML,Lehman SS,Beier-Sexton M,Gillespie JJ,Azad AF
26183 was used in immunocytochemistry to study the role of RalF in Rickettsia entry
Thu Dec 01 00:00:00 EST 2016
PEG3 Interacts with KAP1 through KRAB-A.
PloS one
He H,Ye A,Kim H,Kim J
Published figure using HA Tag monoclonal antibody (Product # 26183) in Immunoprecipitation
Fri Jun 23 00:00:00 EDT 2017
PEG3 Interacts with KAP1 through KRAB-A.
PloS one
He H,Ye A,Kim H,Kim J
Published figure using HA Tag monoclonal antibody (Product # 26183) in Immunoprecipitation
Fri Jun 23 00:00:00 EDT 2017
Structural insights of ZIP4 extracellular domain critical for optimal zinc transport.
Nature communications
Zhang T,Sui D,Hu J
26183 was used in Western Blotting to study how conserved dimeric architecture in ZIP4-ECD is a common structural feature among the LIV-1 proteins.
Mon Jun 20 00:00:00 EDT 2016
CRISPR/Cas9-mediated endogenous C-terminal Tagging of Trypanosoma cruzi Genes Reveals the Acidocalcisome Localization of the Inositol 1,4,5-Trisphosphate Receptor.
The Journal of biological chemistry
Lander N,Chiurillo MA,Storey M,Vercesi AE,Docampo R
26183 was used in immunocytochemistry and western blot to use CRISPR to tag Trypanosoma cruzi genes
Fri Dec 02 00:00:00 EST 2016
MxA Is a Novel Regulator of Endosome-Associated Transcriptional Signaling by Bone Morphogenetic Proteins 4 and 9 (BMP4 and BMP9).
PloS one
Yuan H,Sehgal PB
26183 was used in Western Blotting to identify MxA as a novel stimulator of BMP4 and BMP9 transcriptional signalling.
Thu Jun 22 00:00:00 EDT 2017
MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked.
Scientific reports
Dobó J,Szakács D,Oroszlán G,Kortvely E,Kiss B,Boros E,Szász R,Závodszky P,Gál P,Pál G
26183 was used to show that activated MASP-3 is the exclusive pro-Factor D activator in resting blood
Thu Aug 18 00:00:00 EDT 2016
The Pluripotency Factor NANOG Binds to GLI Proteins and Represses Hedgehog-mediated Transcription.
The Journal of biological chemistry
Li Q,Lex RK,Chung H,Giovanetti SM,Ji Z,Ji H,Person MD,Kim J,Vokes SA
26183 was used in Western Blotting to study the transcriptional response of stem cells to Hedgehog signalling.
Fri Mar 25 00:00:00 EDT 2016
ACTIN-DIRECTED TOXIN. ACD toxin-produced actin oligomers poison formin-controlled actin polymerization.
Science (New York, N.Y.)
Heisler DB,Kudryashova E,Grinevich DO,Suarez C,Winkelman JD,Birukov KG,Kotha SR,Parinandi NL,Vavylonis D,Kovar DR,Kudryashov DS
Fri Jul 31 00:00:00 EDT 2015
Tomato HsfA1a plays a critical role in plant drought tolerance by activating ATG genes and inducing autophagy.
Autophagy
Wang Y,Cai S,Yin L,Shi K,Xia X,Zhou Y,Yu J,Zhou J
26183 was used in ChIP assay and western blot to study the role of plant drought tolerance by activation of ATG genes and inducing autophagy by Tomato HsfA1a
Mon Nov 02 00:00:00 EST 2015
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
Nature
Mazur PK,Reynoird N,Khatri P,Jansen PW,Wilkinson AW,Liu S,Barbash O,Van Aller GS,Huddleston M,Dhanak D,Tummino PJ,Kruger RG,Garcia BA,Butte AJ,Vermeulen M,Sage J,Gozani O
26183 was used in western blot to study the role of MAP3K2 kinase methylation and activation by the SMYD3 lysine methyltransferase in ongogenic Ras signaling
Thu Jun 12 00:00:00 EDT 2014
TRIM29 suppresses TWIST1 and invasive breast cancer behavior.
Cancer research
Ai L,Kim WJ,Alpay M,Tang M,Pardo CE,Hatakeyama S,May WS,Kladde MP,Heldermon CD,Siegel EM,Brown KD
26183 was used in Western Blotting to suggest that TRIM29 acts as a tumour suppressor in breast cancer through its ability to inhibit TWIST1 and suppress epithelial-mesenchymal transition.
Mon Sep 01 00:00:00 EDT 2014
Regulation of the transcriptional activation of the androgen receptor by the UXT-binding protein VHL.
The Biochemical journal
Chen S,Chen K,Zhang Q,Cheng H,Zhou R
26183 was used in immunoprecipitation and western blot to study the mechanism by which the UXT-binding protein VHL modulates androgen receptor transcriptional activation
Fri Nov 15 00:00:00 EST 2013
Valproic acid causes proteasomal degradation of DICER and influences miRNA expression.
PloS one
Zhang Z,Convertini P,Shen M,Xu X,Lemoine F,de la Grange P,Andres DA,Stamm S
26183 was used in western blot to study the proteasomal degradation of DICER and altered miRNA levels induced by valproic acid
Tue Oct 21 00:00:00 EDT 2014
Research resource: identification of novel coregulators specific for thyroid hormone receptor-β2.
Molecular endocrinology (Baltimore, Md.)
Hahm JB,Privalsky ML
26183 was used in immunoprecipitation to identify novel protein co-factors of the beta2 isoform of the thyroid hormone receptor
Wed May 01 00:00:00 EDT 2013
A high-affinity recombinant antibody permits rapid and sensitive direct detection of myeloperoxidase.
Analytical biochemistry
McDonnell B,Hearty S,Finlay WJ,O'Kennedy R
26183 was used in immunoprecipitation to evaluate a recombinant myeloperoxidase antibody
Tue Mar 01 00:00:00 EST 2011
Properties of Nat4, an N(alpha)-acetyltransferase of Saccharomyces cerevisiae that modifies N termini of histones H2A and H4.
Molecular and cellular biology
Polevoda B,Hoskins J,Sherman F
26183 was used in western blot to investigate the properties of Nat4
Mon Jun 01 00:00:00 EDT 2009
Chlamydia attachment to mammalian cells requires protein disulfide isomerase.
Cellular microbiology
Conant CG,Stephens RS
26183 was used in western blot to study the role of cell-surface protein disulfide isomerase in the attachent and infectivity of Chlamydia
Mon Jan 01 00:00:00 EST 2007
Suicide cancer gene therapy using pore-forming toxin, streptolysin O.
Molecular cancer therapeutics
Yang WS,Park SO,Yoon AR,Yoo JY,Kim MK,Yun CO,Kim CW
26183 was used in western blot to study the cancer therapeutic potential of the pore-forming toxin streptolysin O
Thu Jun 01 00:00:00 EDT 2006
