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Immunogen sequence: MKVEVLPALT DNYMYLVIDD ETKEAAIVDP VQPQKVVDAA RKHGVKLTTV LTTHHHWDHA GGNEKLVKLE SGLKVYGGDD RIGALTHKIT HLSTLQVGSL NVKCLATPCH TSGHICYFVS KPGGSEPPAV FTGDTLFVAG CGKFYEGTAD EMCKALLEVL GRLPPDTRVY CGHEYTINNL KFARHVEPGN AAIREKLAWA KEKYSIGEPT VPSTLAEEFT YNPFMRVREK TVQQHAGETD PVTTMRAVRR EKDQFKMPRD; Positive Samples: MCF7, HepG2, Mouse liver, Mouse kidney, Mouse heart, Rat liver, Rat kidney; Cellular Location: Cytoplasm, Mitochondrion matrix
The enzyme encoded by the HAGH gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene. Diseases associated with HAGH include Hydroxyacyl Glutathione Hydrolase Deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Glx II; Glyoxalase II; glyoxylase 2; Hydroxyacylglutathione hydrolase, mitochondrial; hydroxyacylglutathione hydroxylase; Round spermatid protein RSP29
基因别名: BC019817; Glo-2; GLO2; GLX2; GLXII; HAGH; HAGH1; RSP29
UniProt ID: (Human) Q16775, (Mouse) Q99KB8, (Rat) O35952
Entrez Gene ID: (Human) 3029, (Mouse) 14651, (Rat) 24439