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产品信息
PA5-121196
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human HBA2 (NP_000508.1).
偶联物
Unconjugated
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2914768
产品详细信息
Positive test controls include: Mouse liver.
Immunogen sequence: MVLSPADKTN VKAAWGKVGA HAGEYGAEAL ERMFLSFPTT KTYFPHFDLS HGSAQVKGHG KKVADALTNA VAHVDDMPNA LSALSDLHAH KLRVDPVNFK LLSHCLLVTL AAHLPAEFTP AVHASLDKFL ASVSTVLTSK YR
靶标信息
HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2-alpha globin; 2-alpha-1 globin; alpha globin; alpha one globin; alpha-1 globin; alpha-1-globin; Alpha-1/2-globin; alpha-2 globin; alpha-2 globin chain; Alpha-globin; CD31; delta globin; hemoglobin alpha 1 chain; hemoglobin alpha 1 globin chain; hemoglobin alpha 2 chain; Hemoglobin alpha chain; hemoglobin alpha, adult chain 1; hemoglobin alpha, adult chain 2; Hemoglobin alpha-1/2 chain; Hemoglobin subunit alpha; Hemoglobin subunit alpha-1/2; hemoglobin, alpha 1; hemoglobin, alpha 2; mutant hemoglobin alpha 2 globin chain
基因别名: Hba-a1; Hba-a2; HBA-T2; HBA-T3; HBA1; HBA2; HBAM; HBH
UniProt ID: (Human) P69905, (Rat) P01946, (Rat) P33583
Entrez Gene ID: (Human) 3039, (Human) 3040, (Rat) 25632, (Rat) 360504
in utero embryonic development
positive regulation of cell death
response to hydrogen peroxide
hydrogen peroxide catabolic process
erythrocyte development
protein heterooligomerization
oxidation-reduction process
receptor-mediated endocytosis
oxygen transport
bicarbonate transport
cellular oxidant detoxification
negative regulation of blood pressure
regulation of sensory perception of pain
