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产品信息
PA1-7218
产品规格
种属反应
Virus
已发表种属
Not Applicable
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Purified native gp120 from strain IIIB.
偶联物
形式
Liquid
浓度
4-5 mg/mL
纯化类型
IgG fraction
保存液
PBS, pH 7.2
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_559501
产品详细信息
PA1-7218 detects the HIV1 gp120. This antibody does not cross-react with human T or B cells.
PA1-7218 has been successfully used in Western blot and ELISA procedures.
The PA1-7218 immunogen is purified native gp120 from strain IIIB.
Recommended storage of up to 6 months at 2-8ºC. For long term storage, aliquot and freeze. avoiding freeze/thaw cycles.
靶标信息
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: HIV Glycoprotein 120; HIV-1 Glycoprotein 120; Human immunodeficiency virus
