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HNMT Monoclonal Antibody (3G12)

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HNMT Antibody (H00003176-M03) in WB

HNMT monoclonal antibody (M03), clone 3G12. Western Blot analysis of HNMT expression in HeLa.

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产品信息

H00003176-M03

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b, kappa

分类

Monoclonal

类型

Antibody

克隆号

3G12

抗原

HNMT (NP_008826, 184 a.a. approximately 292 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.38 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Cell lysate).

Immunogen sequence: KKYGSRFPQD DLCQYITSDD LTQMLDNLGL KYECYDLLST MDISDCFIDG NENGDLLWDF LTETCNFNAT APPDLRAELG KDLQEPEFSA KKEGKVLFNN TLSFIVIEA

靶标信息

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。