Invitrogen

HNMT Monoclonal Antibody (432CT31.4.2)

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HNMT Antibody (MA5-37557) in WB

Western Blot analysis of HNMT using the HNMT Monoclonal Antibody (Product # MA5-37557) in HepG2 cell line lysates (35 µg/lane).

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产品信息

MA5-37557

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:1,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

432CT31.4.2

抗原

purified His-tagged HNMT protein (fragment)

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Ammonium sulfate precipitation

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2897487

靶标信息

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。