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HOXA10 Antibody (PA5-37866) in IHC (P)
Immunohistochemical analysis of HOXA10 in paraffin embedded human testis using a HOXA10 polyclonal antibody (Product #PA5-37866) at a concentration of 7 µg/mL. Heat induced antigen retrieval was performed with pH 6 buffered citrate. Samples were then stained in horseradish peroxidase.
产品信息
PA5-37866
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence PQATSCSFAQNIKE, from the internal region of HOXA10
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2554474
产品详细信息
This antibody is predicted to react with mouse, pig and cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.
靶标信息
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factorm HOXA10, that may regulate gene expression, morphogenesis, and differentiation. More specifically, HOXA10 may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeo box A10; homeobox protein 1H; Homeobox protein Hox-1.8; Homeobox protein Hox-1H; Homeobox protein Hox-A10; homeobox protein HOXA10; Hox-18; PL
基因别名: HOX1; HOX1.8; HOX1H; HOXA10; PL
UniProt ID: (Human) P31260
Entrez Gene ID: (Human) 3206
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
histone deacetylase binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
skeletal system development
transcription from RNA polymerase II promoter
multicellular organism development
spermatogenesis
single fertilization
male gonad development
anterior/posterior pattern specification
proximal/distal pattern formation
embryonic limb morphogenesis
positive regulation of transcription from RNA polymerase II promoter
uterus development
