Abnova

HOXA5 Monoclonal Antibody (3C2)

查看其他26个HOXA5抗体

抗体检测数据 (2)

HOXA5 Antibody in Immunocytochemistry (ICC/IF)

HOXA5 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 2

HOXA5 Antibody (H00003202-M06) in ICC/IF

Immunofluorescence of monoclonal antibody to HOXA5 on HeLa cell. Antibody concentration is 10 µg/mL.

HOXA5 Antibody in Immunocytochemistry (ICC/IF)

HOXA5 Antibody in ELISA (ELISA)

Product Image Gallery

HOXA5 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescence of monoclonal antibody to HOXA5 on HeLa cell. Antibody concentration is 10 µg/mL.

HOXA5 Antibody in ELISA (ELISA) — Detection limit for recombinant GST tagged HOXA5 is approximately 0.3 ng/mL as a capture antibody.

产品信息

H00003202-M06

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

免疫细胞化学 (ICC/IF)

10 µg/mL

-

酶联免疫吸附实验 (ELISA)

0.3 ng/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b, kappa

分类

Monoclonal

类型

Antibody

克隆号

3C2

抗原

HOXA5 (NP_061975.1, 171 a.a. approximately 270 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: PAQPQIYPWM RKLHISHDNI GGPEGKRART AYTRYQTLEL EKEFHFNRYL TRRRRIEIAH ALCLSERQIK IWFQNRRMKW KKDNKLKSMS MAAAGGAFRP

靶标信息

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: homeo box 1C; homeo box A5; Homeobox protein Hox-1C; Homeobox protein Hox-A5; homeobox protein HOXA5; Hox-1C

查看更多收起

基因别名: HOX1; HOX1.3; HOX1C; HOXA5

查看更多收起

UniProt ID: (Human) Q96CY6

查看更多收起

Entrez Gene ID: (Human) 3202

查看更多收起

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding homeodomain transcription factor

参与通路

respiratory system process transcription from RNA polymerase II promoter anterior/posterior pattern specification positive regulation of receptor biosynthetic process cell migration negative regulation of angiogenesis thyroid gland development regulation of mammary gland epithelial cell proliferation multicellular organism growth positive regulation of apoptotic process positive regulation of myeloid cell differentiation negative regulation of erythrocyte differentiation positive regulation of transcription from RNA polymerase II promoter lung alveolus development embryonic skeletal system morphogenesis bronchiole development epithelial tube branching involved in lung morphogenesis lung goblet cell differentiation lung-associated mesenchyme development trachea cartilage morphogenesis intestinal epithelial cell maturation mesenchymal-epithelial cell signaling mammary gland epithelial cell differentiation mammary gland alveolus development cell-cell signaling involved in mammary gland development