Invitrogen

HOXB2 Polyclonal Antibody

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HOXB2 Antibody (PA5-120690) in WB

Western blot analysis of HOXB2 in mouse kidney. Samples were incubated with HOXB2 Polyclonal antibody (Product # PA5-120690) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

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产品信息

PA5-120690

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:2,000

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 50-140 of human HOXB2 (NP_002136.1).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.67 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2914262

产品详细信息

Positive test controls include: Mouse kidney.

Immunogen sequence: EQTFPSLQPG ASTLQRPRSQ KRAEDGPALP PPPPPPLPAA PPAPEFPWMK EKKSAKKPSQ SATSPSPAAS AVPASGVGSP ADGLGLPEAG G

靶标信息

Hoxb-1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the sonic hedgehog and Mash1 signaling pathways. Hoxb2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. Hoxb2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, Hoxb2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.

仅用于科研。不用于诊断过程。未经明确授权不得转售。