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Immunogen sequence: GSHVHYATSAV FSGGGSFLLS GQVDYAAFGE PGPFPACLKA SADGHPGAFQ TASPAPGTYP KSVSPASGLP AAFSTFEW
Highest antigen sequence identity to the following orthologs - mouse 84%, rat 82%.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA1 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BSAS; homeo box 4G; homeo box A1; homeo box D1; homeobox 1F; homeobox A1; Homeobox protein Hox-D1; Homeobox protein Hox-GG; HOX1; HOX1F; HOX2I; HOXA1; MGC45232
基因别名: Hox-4.7; HOX4; HOX4G; HOXD1
UniProt ID: (Human) Q9GZZ0
Entrez Gene ID: (Human) 3231