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产品信息
PA5-21342
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 218 of HPRT (Uniprot ID#P00492)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11156209
产品详细信息
Recommended positive controls: 293T, A431, HeLa, HepG2, PC-12, Rat2, rat brain.
Predicted reactivity: Rat (97%), Zebrafish (92%), Xenopus laevis (90%), Dog (96%), Pig (97%), Rabbit (98%), Chicken (91%), Chimpanzee (99%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HGPRT; HGPRTase; HPRT 1; HPRT B; hypoxanthine guanine phosphoribosyl transferase 1; hypoxanthine phosphoribosyl transferase; Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 1; testicular tissue protein Li 89
基因别名: C81579; HGPRT; Hgprtase; HPGRT; HPRT; HPRT1
UniProt ID: (Human) P00492, (Mouse) P00493, (Rat) P27605
Entrez Gene ID: (Human) 3251, (Mouse) 15452, (Rat) 24465
nucleotide binding
magnesium ion binding
hypoxanthine phosphoribosyltransferase activity
protein binding
protein homodimerization activity
guanine phosphoribosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
identical protein binding
metal ion binding
glycosyltransferase
response to amphetamine
purine nucleotide biosynthetic process
purine ribonucleoside salvage
adenine salvage
guanine salvage
grooming behavior
locomotory behavior
cytolysis
striatum development
cerebral cortex neuron differentiation
central nervous system neuron development
GMP salvage
IMP salvage
dopamine metabolic process
purine-containing compound salvage
hypoxanthine salvage
positive regulation of dopamine metabolic process
GMP catabolic process
IMP metabolic process
hypoxanthine metabolic process
lymphocyte proliferation
dendrite morphogenesis
protein homotetramerization
nucleoside metabolic process
adenine metabolic process
spermatogenesis
brain development
cellular response to insulin stimulus
