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HRH1 Antibody (PA5-142173) in IHC (P)
Immunohistochemistry analysis of HRH1 in human small intestine, smooth muscle. Samples were incubated with HRH1 polyclonal antibody (Product # PA5-142173) using a dilution of 5 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
产品信息
PA5-142173
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence CNENFKKTFKRILH.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2932831
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
靶标信息
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: H1 receptor; H1-R; H1R; HH1R; Histamine H1 receptor; Histamine H1-R; histamine receptor; histamine receptor, subclass H1
基因别名: H1-R; H1R; HH1R; hisH1; Hisr; HRH1
UniProt ID: (Human) P35367, (Rat) P31390
Entrez Gene ID: (Human) 3269, (Rat) 24448
inflammatory response
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
memory
visual learning
regulation of vasoconstriction
positive regulation of inositol trisphosphate biosynthetic process
regulation of vascular permeability
positive regulation of vasoconstriction
inositol phosphate-mediated signaling
regulation of synaptic plasticity
eosinophil chemotaxis
modulation of synaptic transmission
cellular response to histamine
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
chemical synaptic transmission
response to gravity
negative regulation of steroid biosynthetic process
positive regulation of nitric oxide biosynthetic process
