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产品信息
PA1-24511
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 3rd extracellular domain of human Histamine H2 Receptor
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2121364
产品详细信息
PA1-24511 detects Histamine H2 Receptor in Human samples.
靶标信息
H2 Histamine Receptor stimulates adenylate cyclase activity and leads to the release of acids in the stomach. It is also involved in GI motility and intestinal secretion. Treatments for acid-peptic disorders are based on the inhibition of histamine H2 receptor activity. The 3-untranslated region may be involved in differential expression. Histamine H2 receptor has been reported to be expressed in bone marrow, brain, heart, lymph node, nose, placenta, spinal cord, and stomach. An EST has been isolated from a kidney library.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: gastric receptor 1; Gastric receptor I; H2R; HH2R; Histamine H2 receptor; histamine receptor
基因别名: H2R; HRH2
UniProt ID: (Human) P25021, (Mouse) P97292
Entrez Gene ID: (Human) 3274, (Mouse) 15466
histamine-induced gastric acid secretion
gastrin-induced gastric acid secretion
epithelial cell morphogenesis
immune response
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
memory
visual learning
positive regulation of vasoconstriction
regulation of synaptic plasticity
digestive tract development
gland development
toxin transport
gastric acid secretion
synaptic transmission, dopaminergic
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
sensory perception of chemical stimulus
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
phospholipase C-activating dopamine receptor signaling pathway
negative regulation of arachidonic acid secretion
